ZFIN ID: ZDB-GENE-050517-10
Gene Name: ATP-binding cassette, sub-family B (MDR/TAP), member 7
Gene Symbol: abcb7    Nomenclature History

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Previous Names: fc20c02, wu:fc20c02

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 14 Mapping Details/Browsers
Description: Predicted to have ATPase-coupled transmembrane transporter activity. Predicted to be involved in cellular iron ion homeostasis and transmembrane transport. Predicted to localize to integral component of membrane and mitochondrial inner membrane. Human ortholog(s) of this gene implicated in X-linked sideroblastic anemia with ataxia. Orthologous to human ABCB7 (ATP binding cassette subfamily B member 7).
Genome Resources: Alliance (1),  Gene:566515 (1),  Ensembl(GRCz11):ENSDARG00000062795 (2)
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [IMAGE:6908080]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
High Throughput Expression: GEO (1) Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa407 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa42355 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH abcb7 HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    X-linked sideroblastic anemia with ataxia Alliance Anemia, sideroblastic, with ataxia 301310
    DISEASE ASSOCIATED WITH abcb7 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process transmembrane transport (more)
    Cellular Component integral component of membrane (more)
    Molecular Function ATPase activity (more)
    GO Terms (all 9)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA abcb7-201 (1)    Ensembl 2744
    Browsers: NCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM abcb7 No data available
    MARKER RELATIONSHIPS
    abcb7 Contained in: [BAC] DKEY-33I12 (1) (order this), DKEY-286D7 (1) (order this)
    abcb7 Encodes: [EST] fc20c02, IMAGE:6908080 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:XM_689787 (1) 2758 nt
    Genomic GenBank:AL954179 (1) 194366 nt
    Select Tool
    Polypeptide UniProtKB:E7F6F7 (1) 743 aa
    Sequence Information (all 12)
    ORTHOLOGY for abcb7 ( Chr: 14 )
    CITATIONS (28)