Gene

abca2

ID

ZDB-GENE-050517-1

Name

ATP-binding cassette, sub-family A (ABC1), member 2

Symbol

abca2 Nomenclature History

Previous Names

si:dkey-266h7.1

Type

protein_coding_gene

Location

Chr: 5 Mapping Details/Browsers

Description

Predicted to have ATP binding activity; ATPase activity; and ATPase-coupled transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to localize to integral component of membrane. Orthologous to human ABCA2 (ATP binding cassette subfamily A member 2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With abca2 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		Intellectual developmental disorder with poor growth and with or without seizures or ataxia	618808

Associated With abca2 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR017871	ABC transporter-like, conserved site
Domain	IPR003439	ABC transporter-like, ATP-binding domain
Domain	IPR003593	AAA+ ATPase domain
Domain	IPR013525	ABC-2 type transporter, transmembrane domain
Family	IPR026082	ABC transporter A
Homologous_superfamily	IPR027417	P-loop containing nucleoside triphosphate hydrolase

Domain Details Per Protein

Protein	Length	AAA+ ATPase domain	ABC-2 type transporter, transmembrane domain	ABC transporter A	ABC transporter-like, ATP-binding domain	ABC transporter-like, conserved site	P-loop containing nucleoside triphosphate hydrolase
UniProtKB:A0A8M2BCG2 InterPro	2504
UniProtKB:A0A8M2BCJ8 InterPro	2503
UniProtKB:A0A8M2BCH1 InterPro	2503

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	abca2-202 (1) Ensembl	Ensembl	7,870 nt	Select Tool
mRNA	abca2-203 (1) Ensembl	Ensembl	1,073 nt	Select Tool ZFIN BLAST
mRNA	abca2-204 (1) Ensembl	Ensembl	753 nt	Select Tool ZFIN BLAST
ncRNA	abca2-002 (1) Ensembl	Ensembl	475 nt	Select Tool

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations