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ZIRC
ZFIN ID: ZDB-GENE-050506-73
Gene Name: chloride channel 2c
Gene Symbol: clcn2c
Sequence Ontology ID : SO:0000704

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Previous Names: clc-2c (1), im:6903943 (1), si:ch211-229n1.3

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(Including Attributions)
Location: Chr: 15 Mapping Details/Browsers
Nomenclature History
Note: In pre-publication communications with Alejandro Barrallo Gimeno, it was determined that this gene will be called clcn2c in his upcoming publication.
AUTOMATED DESCRIPTION
Predicted to have voltage-gated chloride channel activity. Involved in chloride ion homeostasis. Localizes to the cell junction. Human ortholog(s) of this gene implicated in idiopathic generalized  ...
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa36004 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa42631 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents:
    DISEASE ASSOCIATED WITH clcn2c HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    idiopathic generalized epilepsy 11 {Epilepsy, idiopathic generalized, susceptibility to, 11} 607628
    {Epilepsy, juvenile absence, susceptibility to, 2} 607628
    {Epilepsy, juvenile myoclonic, susceptibility to, 8} 607628
    primary hyperaldosteronism Hyperaldosteronism, familial, type II 605635
    Leukoencephalopathy with ataxia 615651
    Leukoencephalopathy with ataxia 615651
    Leukoencephalopathy with ataxia 615651
    DISEASE ASSOCIATED WITH clcn2c VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process chloride ion homeostasis (more)
    Cellular Component cell junction (more)
    Molecular Function voltage-gated chloride channel activity (more)
    GO Terms (all 8)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001807 (1)
  • InterPro:IPR014743 (1)
  • Pfam:PF00654 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA clcn2c-201 (1) 2755
    GENE PRODUCT DESCRIPTION No description available
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM clcn2c No data available
    MARKER RELATIONSHIPS
    clcn2cContained in: [BAC] CH211-229N1 (1) (order this)
    clcn2cEncodes: [EST] IMAGE:6903943 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001319271 (1)
    Genomic GenBank:CR381579 (1) 130841bp
    Select Tool
    Polypeptide UniProtKB:E7FCE2 (1) 810aa
    Sequence Information (all 8)
    ORTHOLOGY for clcn2c (Chr: 15)
    CITATIONS (18)