ZFIN ID: ZDB-GENE-050506-24
Gene Name: H2A.Z variant histone 2b
Gene Symbol: h2az2b    Nomenclature History

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Previous Names: h2afvb, h2afvl, im:6896397

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 10 Mapping Details/Browsers
Description: Predicted to have DNA binding activity. Involved in DNA methylation involved in embryo development. Predicted to localize to nuclear chromatin. Orthologous to several human genes including H2AZ1 (H2A.Z variant histone 1).
Genome Resources: Alliance (1),  Gene:403077 (1),  Ensembl(GRCz11):ENSDARG00000116491 (1)
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [IMAGE:6896397]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa18996 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa21818 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-h2az2b N/A 1
    DISEASE ASSOCIATED WITH h2az2b HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH h2az2b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process chromatin organization (more)
    Cellular Component chromosome (more)
    Molecular Function DNA binding (more)
    GO Terms (all 8)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS No data available
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM h2az2b No data available
    MARKER RELATIONSHIPS
    h2az2b Encodes: [EST] IMAGE:6896397 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001043323 (1) 387 nt
    Genomic GenBank:CU633882 (1) 39925 nt
    Select Tool
    Polypeptide UniProtKB:Q7ZU59 (1) 149 aa
    Sequence Information (all 12)
    ORTHOLOGY for h2az2b ( Chr: 10 )
    CITATIONS (26)