Gene

dclk2a

ID
ZDB-GENE-050420-170
Name
doublecortin-like kinase 2a
Symbol
dclk2a Nomenclature History
Previous Names
  • cb572 (1)
  • dclk2
  • zDCLK (1)
  • sb:cb572
  • si:dkey-180n16.1
Type
protein_coding_gene
Location
Chr: 1 Mapping Details/Browsers
Description
Exhibits protein serine/threonine kinase activity. Involved in hyperosmotic response and protein autophosphorylation. Localizes to microtubule cytoskeleton; nucleus; and synaptic vesicle. Is expressed in several structures, including hindbrain neural plate; immature eye; nervous system; optic primordium; and trigeminal placode. Orthologous to human DCLK2 (doublecortin like kinase 2).
Genome Resources
Note
None
Expression
All Expression Data
7 figures from 2 publications
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from Shimomura et al., 2007
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With dclk2a Human Ortholog
No data available
Associated With dclk2a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR008271 Serine/threonine-protein kinase, active site
Binding_site IPR017441 Protein kinase, ATP binding site
Domain IPR000719 Protein kinase domain
Domain IPR003533 Doublecortin domain
Homologous_superfamily IPR011009 Protein kinase-like domain superfamily
Homologous_superfamily IPR036572 Doublecortin domain superfamily
Domain Details Per Protein
Protein Length Doublecortin domain Doublecortin domain superfamily Protein kinase, ATP binding site Protein kinase domain Protein kinase-like domain superfamily Serine/threonine-protein kinase, active site
UniProtKB:A2A125 700
UniProtKB:F1R686 713
UniProtKB:A2A121 810
UniProtKB:A2A124 722
UniProtKB:A0A0G2KZL6 716
UniProtKB:A0A0G2KD98 782
UniProtKB:A2A123 725
UniProtKB:B5DE25 782
UniProtKB:A2A122 791
UniProtKB:A0A0G2L8W3 688
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations