Gene

map3k10

ID
ZDB-GENE-050419-112
Name
mitogen-activated protein kinase kinase kinase 10
Symbol
map3k10 Nomenclature History
Previous Names
  • si:ch211-238g23.2
Type
protein_coding_gene
Location
Chr: 18 Mapping Details/Browsers
Description
Predicted to have JUN kinase kinase kinase activity. Predicted to be involved in activation of JUN kinase activity and positive regulation of apoptotic process. Orthologous to human MAP3K10 (mitogen-activated protein kinase kinase kinase 10).
Genome Resources
Note
None
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With map3k10 Human Ortholog
No data available
Associated With map3k10 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR008271 Serine/threonine-protein kinase, active site
Binding_site IPR017441 Protein kinase, ATP binding site
Domain IPR000719 Protein kinase domain
Domain IPR001245 Serine-threonine/tyrosine-protein kinase, catalytic domain
Domain IPR001452 SH3 domain
Domain IPR035779 MLK1-3, SH3 domain
Family IPR015785 Mitogen-activated protein (MAP) kinase kinase kinase 10
Family IPR016231 Mitogen-activated protein (MAP) kinase kinase kinase, MLK1-4
Homologous_superfamily IPR011009 Protein kinase-like domain superfamily
Homologous_superfamily IPR036028 SH3-like domain superfamily
Domain Details Per Protein
Protein Length Mitogen-activated protein (MAP) kinase kinase kinase 10 Mitogen-activated protein (MAP) kinase kinase kinase, MLK1-4 MLK1-3, SH3 domain Protein kinase, ATP binding site Protein kinase domain Protein kinase-like domain superfamily Serine/threonine-protein kinase, active site Serine-threonine/tyrosine-protein kinase, catalytic domain SH3 domain SH3-like domain superfamily
UniProtKB:F1Q5J2 1062
UniProtKB:F1R5V1 973
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations