Gene

cdk10

ID
ZDB-GENE-050417-94
Name
cyclin-dependent kinase 10
Symbol
cdk10 Nomenclature History
Previous Names
  • zgc:110252 (1)
Type
protein_coding_gene
Location
Chr: 25 Mapping Details/Browsers
Description
Enables kinase activity. Acts upstream of or within histone phosphorylation; negative regulation of neuron apoptotic process; and neurogenesis. Predicted to be active in nucleus. Is expressed in brain; eye; liver; and pleuroperitoneal region. Orthologous to human CDK10 (cyclin dependent kinase 10).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
3 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
6 figures from Yeh et al., 2013
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With cdk10 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Al Kaissi syndrome 617694
Associated With cdk10 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR008271 Serine/threonine-protein kinase, active site
Binding_site IPR017441 Protein kinase, ATP binding site
Domain IPR000719 Protein kinase domain
Domain IPR044093 Cyclin-dependent kinase 10, catalytic domain
Homologous_superfamily IPR011009 Protein kinase-like domain superfamily
Domain Details Per Protein
Protein Length Cyclin-dependent kinase 10, catalytic domain Protein kinase, ATP binding site Protein kinase domain Protein kinase-like domain superfamily Serine/threonine-protein kinase, active site
UniProtKB:Q568J9 275
UniProtKB:F1QKU6 360
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-cdk10 polyclonal IgG Goat
Santa Cruz Biotechnology, Inc.
2
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations