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ZIRC
ZFIN ID: ZDB-GENE-050417-383
Gene Name: serine/threonine kinase 11
Gene Symbol: stk11
Sequence Ontology ID : SO:0001217

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Previous Names: lkb1 (1), wu:fj61a05, zgc:110180

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(Including Attributions)
Location: Chr: 2 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have protein serine/threonine kinase activity. Involved in several processes, including energy homeostasis; glucose homeostasis; and intestinal epithelial cell differentiation. Predicted  ...
GENE EXPRESSION
All Expression Data: 6 figures from 4 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:110180]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
gd15Gt Transgenic Insertion Intron 1 Unknown DNA
hu1960 Point Mutation Unknown Premature Stop ENU
hu1968 Point Mutation Unknown Premature Stop ENU
sa11449 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa18484 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents:
    DISEASE ASSOCIATED WITH stk11 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    pancreatic carcinoma Pancreatic cancer, somatic 260350
    Peutz-Jeghers syndrome Peutz-Jeghers syndrome 175200
    testicular germ cell cancer Testicular tumor, somatic 273300
    Melanoma, malignant, somatic
    DISEASE ASSOCIATED WITH stk11 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process regulation of autophagy (more)
    Cellular Component cytoplasm (more)
    Molecular Function ATP binding (more)
    GO Terms (all 19)
    TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA stk11-201 (1) 2118
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM stk11
    MARKER RELATIONSHIPS
    stk11 Contained in: [Fosmid] CH1073-115E2 (1) (order this), CH1073-391I24 (1) (order this)
    stk11 Encodes: [EST] fj61a05
    [cDNA] MGC:110180 (1) (order this), MGC:192663 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001017839 (1) 2144 bp
    Genomic GenBank:CU693441 (1) 32404 bp
    Select Tool
    Polypeptide UniProtKB:Q568P5 (1) 440 aa
    Sequence Clusters UniGene:1688 (1)
    Sequence Information (all 18)
    ORTHOLOGY for stk11 ( Chr: 2 )
    CITATIONS (28)