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ZIRC
ZFIN ID: ZDB-GENE-050417-177
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Gene Name: aminopeptidase like 1
Gene Symbol: npepl1    Nomenclature History

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Previous Names: wu:fi27h09, wu:fj47h12, zgc:112459 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 6 Mapping Details/Browsers
Description: Predicted to have aminopeptidase activity; manganese ion binding activity; and metalloexopeptidase activity. Predicted to be involved in proteolysis. Predicted to localize to the cytoplasm. Orthologous to human NPEPL1 (aminopeptidase like 1).
Genome Resources: Alliance (1),  Gene:550383 (1),  Ensembl(GRCz11):ENSDARG00000012871 (2)
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:112459]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa8502 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
    • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH npepl1 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH npepl1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process protein metabolic process (more)
    Cellular Component cytoplasm (more)
    Molecular Function aminopeptidase activity (more)
    GO Terms (all 8)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000819 (1)
  • InterPro:IPR011356 (1)
  • InterPro:IPR041417 (1)
  • PROSITE:PS00631 (1)
  • Pfam:PF00883 (1)
  • Pfam:PF18295 (1)
    • TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA npepl1-201 (1)    Ensembl 2193
    Select Tool
    Browsers: UCSC,  NCBI,  Ensembl,  ZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM npepl1 No data available
    MARKER RELATIONSHIPS
    npepl1 Contained in: [BAC] DKEY-249D8 (1) (order this)
    [Fosmid] CH1073-298I18 (1) (order this)
    npepl1 Encodes: [EST] fi27h09, fj47h12
    [cDNA] MGC:112459 (1) (order this), MGC:174290 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001017688 (1) 1635 bp
    Select Tool
    Genomic GenBank:CU467627 (1) 35464 bp
    Select Tool
    Polypeptide UniProtKB:A9JT03 (1) 525 aa
    Select Tool
    Sequence Clusters UniGene:935 (1)
    Sequence Information (all 20)
    ORTHOLOGY for npepl1 ( Chr: 6 )
    CITATIONS (19)