ZFIN ID: ZDB-GENE-050411-72
Gene Name: myosin VAb
Gene Symbol: myo5ab    Nomenclature History

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Previous Name: im:7152131

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 25 Mapping Details/Browsers
Description: Predicted to have ATP binding activity; actin filament binding activity; and motor activity. Predicted to localize to the myosin complex. Human ortholog(s) of this gene implicated in Griscelli syndrome type 1. Orthologous to human MYO5A (myosin VA).
Genome Resources: Alliance (1),  Gene:565267 (1),  Ensembl(GRCz11):ENSDARG00000025218 (1)
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [IMAGE:7152131]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
PHENOTYPE No data available
DISEASE ASSOCIATED WITH myo5ab HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Griscelli syndrome type 1 Alliance Griscelli syndrome, type 1 214450
DISEASE ASSOCIATED WITH myo5ab VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Cellular Component myosin complex (more)
Molecular Function actin binding (more)
GO Terms (all 6)
PROTEIN FAMILIES, DOMAINS AND SITES
Type InterPro ID Name
Binding_site IPR000048 IQ motif, EF-hand binding site
Domain IPR001609 Myosin head, motor domain
Domain IPR002710 Dilute domain
Homologous_superfamily IPR008989 Myosin S1 fragment, N-terminal
Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
Domain IPR036103 Class V myosin, motor domain
Homologous_superfamily IPR036961 Kinesin motor domain superfamily
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA myo5ab-202 (1)    Ensembl 3582
Browsers: NCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM myo5ab No data available
MARKER RELATIONSHIPS
myo5ab Contained in: [BAC] CH211-286C4 (1)
myo5ab Encodes: [EST] IMAGE:7152131 (1)
SEQUENCE INFORMATION
Type Accession # Length (bp/aa) Analysis
RNA RefSeq:XM_009297774 (1)
Genomic GenBank:BX088562 (1) 138646 bp
Select Tool
Polypeptide UniProtKB:E7FB39 (1) 1823 aa
Sequence Information (all 8)
ORTHOLOGY for myo5ab ( Chr: 25 )
CITATIONS (15)