ZFIN ID: ZDB-GENE-050411-55
Gene Name: integrin, alpha 3b
Gene Symbol: itga3b    Nomenclature History

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Previous Names: bdf (1), fyd (1), itga3 (1), badfin (1), frayed, im:7145180 (1), im:7155971 (1), unm tz296, unm_tz296

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 12 Mapping Details/Browsers
Description: Involved in fin morphogenesis. Predicted to localize to integrin complex. Is expressed in several structures, including cardiovascular system; nervous system; periderm; pharyngeal arch; and pronephros. Orthologous to human ITGA3 (integrin subunit alpha 3).
Genome Resources: Alliance (1),  Gene:100331874 (1),  Ensembl(GRCz11):ENSDARG00000012824 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
fr21 Point Mutation Unknown Missense ENU
sa22024 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa31854 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa35203 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • tj2b Unknown Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • tz296 Small Deletion Acceptor Splice Site of Exon 10 Cryptic Acceptor Splice Site, Frameshift, Premature Stop
  • European Zebrafish Resource Center (EZRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-itga3b N/A 4
    MO2-itga3b N/A 3
    DISEASE ASSOCIATED WITH itga3b HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    Interstitial lung disease, nephrotic syndrome, and epidermolysis bullosa, congenital 614748
    DISEASE ASSOCIATED WITH itga3b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process fin development (more)
    Cellular Component integral component of membrane (more)
    GO Terms (all 7)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA itga3b-201 (1)    Ensembl 3529
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM itga3b No data available
    MARKER RELATIONSHIPS
    itga3b Contained in: [BAC] CH73-209K3 (1), CH211-271E19 (1)
    itga3b Encodes: [EST] IMAGE:7145180 (1), IMAGE:7155971 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001190309 (1) 3556 nt
    Genomic GenBank:CU468219 (1) 126695 nt
    Select Tool
    Polypeptide UniProtKB:D7PS99 (1) 1041 aa
    Sequence Information (all 19)
    ORTHOLOGY for itga3b ( Chr: 12 )
    CITATIONS (32)