ZFIN ID: ZDB-GENE-050410-4
Gene Name: actin related protein 2b
Gene Symbol: actr2b    Nomenclature History

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Previous Name: zgc:110550 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 13 Mapping Details/Browsers
Description: Predicted to contribute to actin filament binding activity. Involved in primitive erythrocyte differentiation. Predicted to localize to actin cytoskeleton; nucleus; and site of double-strand break. Orthologous to human ACTR2 (actin related protein 2).
Genome Resources: Alliance (1),  Gene:554861 (1),  Ensembl(GRCz11):ENSDARG00000070076 (2)
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:110550]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa13493 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-actr2b
    1
    CRISPR2-actr2b
    1
    CRISPR3-actr2b
    1
    CRISPR4-actr2b
    1
    MO1-actr2b N/A 1
    MO2-actr2b N/A 1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH actr2b HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH actr2b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process primitive erythrocyte differentiation (more)
    Cellular Component Arp2/3 protein complex (more)
    Molecular Function actin binding (more)
    GO Terms (all 16)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA actr2b-201 (1)    Ensembl 1343
    actr2b-202 (1)    Ensembl 828
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM actr2b No data available
    MARKER RELATIONSHIPS
    actr2b Contained in: [BAC] DKEY-66M17 (1) (order this)
    actr2b Encodes: [cDNA] MGC:110550 (1), MGC:174305 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001017542 (1) 1365 nt
    Genomic GenBank:BX629343 (1) 207677 nt Blast at MegaBLAST
    Polypeptide UniProtKB:Q56A35 (1) 394 aa
    Sequence Information (all 20)
    ORTHOLOGY for actr2b ( Chr: 13 )
    CITATIONS (26)