ZFIN ID: ZDB-GENE-050320-94
Gene Name: lens intrinsic membrane protein 2.5
Gene Symbol: lim2.5    Nomenclature History

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Previous Names: mp19-5 (1), zgc:103621

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 16 Mapping Details/Browsers
Description: Predicted to be a structural constituent of eye lens. Predicted to localize to plasma membrane. Human ortholog(s) of this gene implicated in cataract and cataract 19 multiple types. Orthologous to human LIM2 (lens intrinsic membrane protein 2).
Genome Resources: Alliance (1),  Gene:541395 (1),  Ensembl(GRCz11):ENSDARG00000041295 (1)
GENE EXPRESSION No data available
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa13298 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH lim2.5 HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    cataract 19 multiple types Alliance Cataract 19, multiple types 615277
    DISEASE ASSOCIATED WITH lim2.5 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process biological_process (more)
    Cellular Component integral component of membrane (more)
    Molecular Function structural constituent of eye lens (more)
    GO Terms (all 5)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA lim2.5-201 (1)    Ensembl 1108
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM lim2.5 No data available
    MARKER RELATIONSHIPS
    lim2.5 Contained in: [BAC] CH211-231M23 (1)
    lim2.5 Encodes: [cDNA] MGC:103621 (1), MGC:192063 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001013522 (1) 900 nt
    Genomic GenBank:CU855686 (1) 137702 nt
    Select Tool
    Polypeptide UniProtKB:Q5BKW4 (1) 173 aa
    Sequence Information (all 15)
    ORTHOLOGY for lim2.5 ( Chr: 16 )
    CITATIONS (16)