ZFIN ID: ZDB-GENE-050320-86
Gene Name: musashi RNA-binding protein 1
Gene Symbol: msi1    Nomenclature History

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Previous Names: fb40b12, wu:fb40b12, zgc:103751

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 8 Mapping Details/Browsers
Description: Predicted to have RNA binding activity. Involved in central nervous system development. Predicted to localize to the cytoplasm; nucleus; and polysome. Is expressed in central nervous system; eye; and immature eye. Orthologous to human MSI1 (musashi RNA binding protein 1).
Genome Resources: Alliance (1),  Gene:541389 (1),  Ensembl(GRCz11):ENSDARG00000010710 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la010184Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la026548Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la026549Tg Transgenic Insertion Unknown Unknown DNA
    Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-msi1 N/A 1
    MO2-msi1 N/A 1
    DISEASE ASSOCIATED WITH msi1 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH msi1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process central nervous system development (more)
    Cellular Component cytoplasm (more)
    Molecular Function nucleic acid binding (more)
    GO Terms (all 8)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Domain IPR000504 RNA recognition motif domain
    Homologous_superfamily IPR012677 Nucleotide-binding alpha-beta plait domain superfamily
    Domain IPR034126 RNA-binding protein Musashi homologue, RNA recognition motif 2
    Homologous_superfamily IPR035979 RNA-binding domain superfamily
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA msi1-201 (1)    Ensembl 2176
    msi1-202 (1)    Ensembl 644
    msi1-204 (1)    Ensembl 807
    ncRNA msi1-002 (1)    Ensembl 719
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    Name Type Isotype Host Organism Assay Source Publications
    Ab1-msi1 polyclonal Rabbit 1
    Ab2-msi1 monoclonal Rat WB 1
    Ab3-msi1 polyclonal Rabbit IHC 1
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM msi1 No data available
    MARKER RELATIONSHIPS
    msi1 Contained in: [BAC] DKEY-63D15 (1) (order this)
    msi1 Encodes: [EST] fb40b12
    [cDNA] MGC:103751 (1), MGC:191536 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001013516 (1) 2309 bp
    Genomic GenBank:BX005328 (1) 272840 bp Blast at MegaBLAST
    Polypeptide UniProtKB:J4C3V8 (1) 349 aa
    Sequence Information (all 25)
    ORTHOLOGY for msi1 ( Chr: 8 )
    CITATIONS (33)