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ZIRC
ZFIN ID: ZDB-GENE-050320-35
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Gene Name: peroxiredoxin 1
Gene Symbol: prdx1
Sequence Ontology ID : SO:0001217

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Previous Names: hm:zehl0637, zgc:110343 (1)

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(Including Attributions)
Location: Chr: 2 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have thioredoxin peroxidase activity. Involved in leukocyte activation. Localizes to the protein-containing complex. Human ortholog(s) of this gene implicated in methylmalonic aciduria  ...
GENE EXPRESSION
All Expression Data: 18 figures from 9 publications
Directly Submitted Expression Data: 5 figures (7 images) from Thisse et al., 2004 [IMAGE:7148899]
Wild-type Stages, Structures: Gastrula:75%-epiboly (8.0h-9.0h) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Targeting reagents:
PHENOTYPE No data available
DISEASE ASSOCIATED WITH prdx1 HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
methylmalonic aciduria and homocystinuria type cblC Methylmalonic aciduria and homocystinuria, cblC type, digenic 277400
DISEASE ASSOCIATED WITH prdx1 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process leukocyte activation (more)
Cellular Component protein-containing complex (more)
Molecular Function antioxidant activity (more)
GO Terms (all 12)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000866 (1)
  • InterPro:IPR013766 (1)
  • InterPro:IPR019479 (1)
  • InterPro:IPR024706 (1)
  • InterPro:IPR036249 (1)
  • PROSITE:PS51352 (1)
  • Pfam:PF00578 (1)
  • Pfam:PF10417 (1)
    • TRANSCRIPTS
    Type Name Length (bp) Analysis
    ncRNA prdx1-003 (1) 627
    Select Tool
    mRNA prdx1-201 (1) 1224
    Select Tool
    prdx1-202 (1) 933
    Select Tool
    GENE PRODUCT DESCRIPTION No description available
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM prdx1 No data available
    MARKER RELATIONSHIPS
    prdx1 Contained in: [BAC] CH73-182A11 (1) (order this), CH211-284B7 (1) (order this)
    prdx1 Encodes: [EST] IMAGE:7148899 (1) (order this), zehl0637
    [cDNA] MGC:110343 (1) (order this), MGC:173697 (1) (order this), MGC:192175 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001013471 (1) 1100 bp
    Select Tool
    Genomic GenBank:AL954171 (1) 148854 bp
    Select Tool
    Polypeptide UniProtKB:A7MCD6 (1) 201 aa
    Select Tool
    Sequence Clusters UniGene:81710 (1)
    Sequence Information (all 26)
    OTHER prdx1 GENE PAGES
  • Alliance (1)
  • Gene:541344 (1)
  • VEGA:OTTDARG00000019363 (1)
  • Ensembl(GRCz11):ENSDARG00000058734 (2)
    • ORTHOLOGY for prdx1 ( Chr: 2 )
    CITATIONS (52)