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General Information
ZIRC
ZFIN ID: ZDB-GENE-050317-1
Gene Name: tumor necrosis factor a (TNF superfamily, member 2)
Gene Symbol: tnfa
Sequence Ontology ID : SO:0001217

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Attributions

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Previous Names: TNF1 (1), TNF-alpha 1 (1), tnf-alpha

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(Including Attributions)
Location: Chr: 19 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have cytokine activity and tumor necrosis factor receptor binding activity. Involved in several processes, including fin regeneration; intestinal epithelial structure maintenance; and  ...
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
ihb497 Indel Exon 1 Unknown CRISPR
sa16250 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa43296 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents:
    PHENOTYPE
    Data: 3 figures from 3 publications
    Observed in:
    DISEASE ASSOCIATED WITH tnfa HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    migraine {Migraine without aura, susceptibility to} 157300
    {Asthma, susceptibility to} 600807
    {Dementia, vascular, susceptibility to}
    {Malaria, cerebral, susceptibility to} 611162
    {Septic shock, susceptibility to}
    DISEASE ASSOCIATED WITH tnfa VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process defense response to bacterium (more)
    Cellular Component extracellular space (more)
    Molecular Function cytokine activity (more)
    GO Terms (all 20)
    TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA tnfa-201 (1) 1048
     Withdrawn Transcriptsextinct
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM tnfa
    MARKER RELATIONSHIPS
    tnfa Contained in: [BAC] CH73-361O3 (1) (order this), CH211-127D20 (1) (order this), CH211-176D22 (1) (order this)
    tnfa Encodes: [cDNA] MGC:152825 (1) (order this), MGC:192241 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_212859 (1) 1145 bp
    Genomic GenBank:BX469886 151598 bp
    Select Tool
    Polypeptide UniProtKB:Q08CQ3 (1) 234 aa
    Sequence Clusters UniGene:89727 (1)
    Sequence Information (all 19)
    ORTHOLOGY for tnfa ( Chr: 19 )
    CITATIONS (401)