ZFIN ID: ZDB-GENE-050309-25
Gene Name: NADH:ubiquinone oxidoreductase subunit B11
Gene Symbol: ndufb11    Nomenclature History

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Previous Names: im:6897973 (1), si:dkey-6n6.4 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 8 Mapping Details/Browsers
Description: Involved in heart development and vasculature development. Predicted to localize to mitochondrial respiratory chain complex I. Is expressed in several structures, including alar plate midbrain region; digestive system; intestinal bulb primordium; optic tectum; and pectoral fin. Human ortholog(s) of this gene implicated in mitochondrial complex I deficiency. Orthologous to human NDUFB11 (NADH:ubiquinone oxidoreductase subunit B11).
Genome Resources: Alliance (1),  Gene:562219 (1),  Ensembl(GRCz11):ENSDARG00000043467 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Sequence Targeting Reagents
Targeting Reagent Created Alleles Publications
MO1-ndufb11 N/A 1
MO2-ndufb11 N/A 1
DISEASE ASSOCIATED WITH ndufb11 HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
linear skin defects with multiple congenital anomalies 3 Alliance Linear skin defects with multiple congenital anomalies 3 300952
?Mitochondrial complex I deficiency, nuclear type 30 301021
DISEASE ASSOCIATED WITH ndufb11 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process heart development (more)
Cellular Component integral component of membrane (more)
Molecular Function molecular_function (more)
GO Terms (all 5)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA ndufb11-201 (1)    Ensembl 816
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM ndufb11 No data available
MARKER RELATIONSHIPS
ndufb11 Contained in: [BAC] DKEY-6N6 (1) (order this)
ndufb11 Encodes: [EST] IMAGE:6897973 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_001044981 (1) 816 nt
Genomic GenBank:BX004884 (1) 225442 nt Blast at MegaBLAST
Polypeptide UniProtKB:Q1LYN0 (1) 150 aa
Sequence Information (all 7)
ORTHOLOGY for ndufb11 ( Chr: 8 )
CITATIONS (20)