ZFIN ID: ZDB-GENE-050309-102
Gene Name: intersectin 2b
Gene Symbol: itsn2b    Nomenclature History

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Previous Names: im:7149072 (1), si:ch211-175f11.2 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 17 Mapping Details/Browsers
Description: Predicted to have molecular adaptor activity. Predicted to be involved in clathrin-dependent synaptic vesicle endocytosis. Predicted to localize to several cellular components, including clathrin-coated pit; intracellular vesicle; and presynaptic membrane. Orthologous to human ITSN2 (intersectin 2).
Genome Resources: Alliance (1),  Gene:445153 (1),  Ensembl(GRCz11):ENSDARG00000054973 (1)
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [IMAGE:7149072]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa11862 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa18555 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa23111 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa23112 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa25044 Point Mutation Unknown Premature Stop ENU
    sa32157 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa32158 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa32159 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa36447 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa42958 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH itsn2b HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH itsn2b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process endocytosis (more)
    Cellular Component clathrin-coated pit (more)
    Molecular Function calcium ion binding (more)
    GO Terms (all 7)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA itsn2b-201 (1)    Ensembl 6492
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM itsn2b No data available
    MARKER RELATIONSHIPS
    itsn2b Contained in: [BAC] CH211-175F11 (1), DKEY-190L8 (1) (order this)
    itsn2b Encodes: [EST] IMAGE:7149072 (1)
    itsn2b Is Hybridized by: [cDNA] MGC:100816 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001003547 (1) 6493 nt
    Genomic GenBank:CR628334 (1) 147890 nt
    Select Tool
    Polypeptide UniProtKB:F1R0Z9 (1) 1741 aa
    Sequence Information (all 18)
    ORTHOLOGY for itsn2b ( Chr: 17 )
    CITATIONS (16)