Gene

hapln1a

ID

ZDB-GENE-050302-175

Name

hyaluronan and proteoglycan link protein 1a

Symbol

hapln1a Nomenclature History

Previous Names

crtl1 (1)
hapln1
fc26f11
fc37g04
fc50e12
fc55h01
wu:fc26f11 (1)
wu:fc37g04 (1)
wu:fc50e12 (1)
wu:fc55h01 (1)

Type

protein_coding_gene

Location

Chr: 5 Mapping Details/Browsers

Description

Predicted to have hyaluronic acid binding activity. Involved in fin regeneration. Predicted to localize to extracellular matrix. Is expressed in several structures, including adaxial cell; hypochord; notochord; pharyngeal arch; and rhombomere. Orthologous to human HAPLN1 (hyaluronan and proteoglycan link protein 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

17 figures from 9 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 2 figures from Derrick et al., 2021
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With hapln1a Human Ortholog

No data available

Associated With hapln1a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000538	Link domain
Domain	IPR003599	Immunoglobulin subtype
Domain	IPR007110	Immunoglobulin-like domain
Domain	IPR013106	Immunoglobulin V-set domain
Homologous_superfamily	IPR013783	Immunoglobulin-like fold
Homologous_superfamily	IPR016186	C-type lectin-like/link domain superfamily
Homologous_superfamily	IPR016187	C-type lectin fold
Homologous_superfamily	IPR036179	Immunoglobulin-like domain superfamily

Domain Details Per Protein

Protein	Length	C-type lectin fold	C-type lectin-like/link domain superfamily	Immunoglobulin-like domain	Immunoglobulin-like domain superfamily	Immunoglobulin-like fold	Immunoglobulin subtype	Immunoglobulin V-set domain	Link domain
UniProtKB:Q1LXE1 InterPro	336
UniProtKB:B3DIH3 InterPro	328

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	hapln1a-201 (1) Ensembl	Havana	585 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	hapln1a-202 (1) Ensembl	Havana	4922 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Interactions and Pathways

No data available

Antibodies

Name	Type	Antigen Genes	Isotype	Host Organism	Assay	Source	Citations
Ab2-HAPLN1a	polyclonal	hapln1a		Rabbit	IHC	Proteintech	1

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations