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ZIRC
ZFIN ID: ZDB-GENE-050302-113
Gene Name: neuregulin 1
Gene Symbol: nrg1
Sequence Ontology ID : SO:0001217

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Previous Name: wu:fm70e01

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(Including Attributions)
Location: Chr: 10 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have signaling receptor binding activity. Involved in several processes, including fin regeneration; nervous system development; and ventricular trabecula myocardium morphogenesis.  ...
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
bns101 Small Deletion Exon 2 Frameshift, Premature Stop TALEN
hg114 Small Deletion Unknown Unknown CRISPR
la017618Tg Transgenic Insertion Unknown Unknown DNA
la027207Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • nc26 Small Deletion Exon 6 Frameshift, Premature Stop CRISPR
    nc27 Small Deletion Exon 6 Frameshift, Premature Stop CRISPR
    nc28 Indel Exon 3 Frameshift, Premature Stop CRISPR
    nc29 Indel Exon 3 Frameshift, Premature Stop CRISPR
    sa45389 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • z26 Point Mutation Unknown Unknown
    Targeting reagents:
    DISEASE ASSOCIATED WITH nrg1 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    schizophrenia 6 {?Schizophrenia, susceptibility to} 603013
    DISEASE ASSOCIATED WITH nrg1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process neural crest cell migration (more)
    Cellular Component integral component of membrane (more)
    Molecular Function signaling receptor binding (more)
    GO Terms (all 17)
    TRANSCRIPTS
    Type Name Length (bp) Analysis
    ncRNA nrg1-002 (1) 511
    mRNA nrg1-202 (1) 2193
    nrg1-204 (1) 2991
    nrg1-205 (1) 2645
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    PLASMIDS No data available
    MARKER RELATIONSHIPS
    nrg1 Contained in: [BAC] CH73-386K7 (1) (order this), DKEY-237I12 (1) (order this), DKEYP-45E9 (1), DKEYP-73E12 (1)
    nrg1 Encodes: [EST] fm70e01
    [cDNA] MGC:195082 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001044911 (1) 2653 bp
    Genomic GenBank:BX537303 (1) 204522 bp Blast at MegaBLAST
    Polypeptide UniProtKB:A0A0R4IBM0 (1) 730 aa
    Sequence Clusters UniGene:133124 (1)
    Sequence Information (all 66)
    ORTHOLOGY for nrg1 ( Chr: 10 )
    CITATIONS (55)