ZFIN ID: ZDB-GENE-050302-10
Gene Name: PHD finger protein 2
Gene Symbol: phf2    Nomenclature History

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Previous Names: phf8, im:4200679, wu:fa14c10

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 11 Mapping Details/Browsers
Description: Predicted to have several functions, including histone demethylase activity (H3-K9 specific); transcription coactivator activity; and transition metal ion binding activity. Predicted to be involved in negative regulation of ribosomal DNA heterochromatin assembly. Predicted to localize to kinetochore and nucleolus. Orthologous to human PHF2 (PHD finger protein 2).
Genome Resources: Alliance (1),  Gene:503778 (1),  Ensembl(GRCz11):ENSDARG00000018691 (2)
GENE EXPRESSION
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la011990Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa9456 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-phf2 N/A 1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH phf2 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH phf2 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process negative regulation of ribosomal DNA heterochromatin assembly (more)
    Cellular Component kinetochore (more)
    Molecular Function histone demethylase activity (H3-K9 specific) (more)
    GO Terms (all 17)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA phf2-201 (1)    Ensembl 5745
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM phf2 No data available
    MARKER RELATIONSHIPS
    phf2 Contained in: [BAC] DKEY-14F19 (1) (order this)
    phf2 Encodes: [EST] fa14c10 (1), IMAGE:4200679
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001202418 (1) 3588 nt
    Genomic GenBank:BX601648 (1) 230457 nt Blast at MegaBLAST
    Polypeptide UniProtKB:F1Q721 (1) 1075 aa
    Sequence Information (all 15)
    ORTHOLOGY for phf2 ( Chr: 11 )
    CITATIONS (24)