Gene

il4r.1

ID
ZDB-GENE-050227-5
Name
interleukin 4 receptor, tandem duplicate 1
Symbol
il4r.1 Nomenclature History
Previous Names
  • il4r
  • DrIL-4Ralpha (1)
  • il-4alpha (1)
  • zgc:113063
Type
protein_coding_gene
Location
Chr: 3 Mapping Details/Browsers
Description
Exhibits interleukin-4 binding activity. Involved in neurogenesis and regeneration. Localizes to plasma membrane. Human ortholog(s) of this gene implicated in several diseases, including acne; allergic conjunctivitis; human immunodeficiency virus infectious disease; multiple sclerosis (multiple); and renal tuberculosis. Is expressed in several structures, including digestive system; gill; immune system; integument; and ovary. Orthologous to human IL4R (interleukin 4 receptor).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
7 figures from 6 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With il4r.1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
{AIDS, slow progression to} 609423
{Atopy, susceptibility to} 147050
Associated With il4r.1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR015319 Interleukin-4 receptor alpha, N-terminal
Homologous_superfamily IPR013783 Immunoglobulin-like fold
Homologous_superfamily IPR036116 Fibronectin type III superfamily
Domain Details Per Protein
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-il4r.1 IgM Rabbit
  • IHC
1
Ab2-il4r.1 Mouse
  • IHC
1
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations