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ZIRC
ZFIN ID: ZDB-GENE-050227-5
Gene Name: interleukin 4 receptor, tandem duplicate 1
Gene Symbol: il4r.1
Sequence Ontology ID : SO:0001217

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Previous Names: il4r, DrIL-4Ralpha (1), il-4alpha (1), zgc:113063

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(Including Attributions)
Location: Chr: 3 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Exhibits interleukin-4 binding activity. Involved in neurogenesis and regeneration. Localizes to the plasma membrane. Human ortholog(s) of this gene implicated in several diseases, including acne;  ...
GENE EXPRESSION
All Expression Data: 7 figures from 6 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:113063]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa17544 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa20105 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents:
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH il4r.1 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    {AIDS, slow progression to} 609423
    {Atopy, susceptibility to} 147050
    DISEASE ASSOCIATED WITH il4r.1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process neurogenesis (more)
    Cellular Component plasma membrane (more)
    Molecular Function interleukin-4 binding (more)
    GO Terms (all 8)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR013783 (1)
  • InterPro:IPR015319 (1)
  • InterPro:IPR036116 (1)
  • Pfam:PF09238 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA il4r.1-203 (1) 1250
    GENE PRODUCT DESCRIPTION No description available
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM il4r.1 No data available
    MARKER RELATIONSHIPS
    il4r.1 Contained in: [BAC] DKEY-6E3 (1) (order this)
    il4r.1 Encodes: [cDNA] MGC:113063 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001013282 (1) 1140 bp
    Genomic GenBank:BX571715 (1) 141705 bp
    Select Tool
    Polypeptide UniProtKB:A0A0N4STT3 (1) 624 aa
    Sequence Clusters UniGene:87659 (1)
    Sequence Information (all 27)
    OTHER il4r.1 GENE PAGES
  • Alliance (1)
  • Gene:503594 (1)
  • VEGA:OTTDARG00000021864 (1)
  • ORTHOLOGY for il4r.1 ( Chr: 3 )
    CITATIONS (21)