Gene

fbxl22

ID
ZDB-GENE-050227-1
Name
F-box and leucine-rich repeat protein 22
Symbol
fbxl22 Nomenclature History
Previous Names
  • zgc:110743
Type
protein_coding_gene
Location
Chr: 25 Mapping Details/Browsers
Description
Involved in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process and regulation of cardiac muscle cell contraction. Predicted to localize to SCF ubiquitin ligase complex. Orthologous to human FBXL22 (F-box and leucine rich repeat protein 22).
Genome Resources
Note
None
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
3 figures from Spaich et al., 2012
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With fbxl22 Human Ortholog
No data available
Associated With fbxl22 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001810 F-box domain
Homologous_superfamily IPR032675 Leucine-rich repeat domain superfamily
Homologous_superfamily IPR036047 F-box-like domain superfamily
Repeat IPR006553 Leucine-rich repeat, cysteine-containing subtype
Domain Details Per Protein
Protein Length F-box domain F-box-like domain superfamily Leucine-rich repeat, cysteine-containing subtype Leucine-rich repeat domain superfamily
UniProtKB:F1R1F0 227
UniProtKB:Q5EAS7 227
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Gene Tree
Ensembl
Citations