ZFIN ID: ZDB-GENE-050221-3
Gene Name: discs, large homolog 2 (Drosophila)
Gene Symbol: dlg2    Nomenclature History

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Previous Name: PSD-93 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 10 Mapping Details/Browsers
Description: Predicted to be involved in several processes, including establishment or maintenance of epithelial cell apical/basal polarity; negative regulation of phosphatase activity; and receptor clustering. Predicted to colocalize with ionotropic glutamate receptor complex. Is expressed in nervous system and neural tube. Orthologous to human DLG2 (discs large MAGUK scaffold protein 2).
Genome Resources: Alliance (1),  Gene:497638 (1),  Ensembl(GRCz11):ENSDARG00000099323 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa21759 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa34928 Point Mutation Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH dlg2 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH dlg2 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process negative regulation of phosphatase activity (more)
    Cellular Component axon (more)
    GO Terms (all 18)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA dlg2-201 (1)    Ensembl 2788
    dlg2-202 (1)    Ensembl 586
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM dlg2 No data available
    MARKER RELATIONSHIPS
    dlg2 Contained in: [BAC] CH73-192G7 (1), CH211-189P14 (1), CH211-271C2 (1), CH211-285K18 (1), DKEY-97K19 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001012378 (1) 2714 nt
    Genomic GenBank:BX470178 (1) 166954 nt
    Select Tool
    Polypeptide UniProtKB:Q5PYH7 (1) 881 aa
    Sequence Information (all 80)
    ORTHOLOGY for dlg2 ( Chr: 10 )
    CITATIONS (21)