Gene

dlg2

ID
ZDB-GENE-050221-3
Name
discs, large homolog 2 (Drosophila)
Symbol
dlg2 Nomenclature History
Previous Names
  • PSD-93 (1)
Type
protein_coding_gene
Location
Chr: 10 Mapping Details/Browsers
Description
Predicted to be involved in several processes, including establishment or maintenance of epithelial cell apical/basal polarity; negative regulation of phosphatase activity; and receptor clustering. Predicted to colocalize with ionotropic glutamate receptor complex. Is expressed in nervous system and neural tube. Orthologous to human DLG2 (discs large MAGUK scaffold protein 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
3 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With dlg2 Human Ortholog
No data available
Associated With dlg2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR020590 Guanylate kinase, conserved site
Domain IPR001452 SH3 domain
Domain IPR001478 PDZ domain
Domain IPR008144 Guanylate kinase-like domain
Domain IPR008145 Guanylate kinase/L-type calcium channel beta subunit
Domain IPR019583 PDZ-associated domain of NMDA receptors
Domain IPR019590 Disks large homologue 1, N-terminal PEST domain
Domain IPR035759 Disks Large homologue 2, SH3 domain
Family IPR016313 Disks large 1-like
Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
Homologous_superfamily IPR036028 SH3-like domain superfamily
Homologous_superfamily IPR036034 PDZ superfamily
Domain Details Per Protein
Protein Length Disks large 1-like Disks large homologue 1, N-terminal PEST domain Disks Large homologue 2, SH3 domain Guanylate kinase, conserved site Guanylate kinase-like domain Guanylate kinase/L-type calcium channel beta subunit PDZ-associated domain of NMDA receptors PDZ domain PDZ superfamily P-loop containing nucleoside triphosphate hydrolase SH3 domain SH3-like domain superfamily
UniProtKB:A0A0R4ISR6 195
UniProtKB:Q5PYH7 881
UniProtKB:A0A0R4IU29 862
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations