Gene
dlg2
- ID
- ZDB-GENE-050221-3
- Name
- discs, large homolog 2 (Drosophila)
- Symbol
- dlg2 Nomenclature History
- Previous Names
-
- PSD-93 (1)
- Type
- protein_coding_gene
- Location
- Chr: 10 Mapping Details/Browsers
- Description
- Predicted to be involved in several processes, including establishment or maintenance of epithelial cell apical/basal polarity; receptor clustering; and receptor localization to synapse. Predicted to be located in several cellular components, including axon; perikaryon; and synapse. Predicted to be active in several cellular components, including basolateral plasma membrane; neuromuscular junction; and postsynaptic density membrane. Is expressed in nervous system and neural tube. Orthologous to human DLG2 (discs large MAGUK scaffold protein 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR020590 | Guanylate kinase, conserved site |
| Domain | IPR001452 | SH3 domain |
| Domain | IPR001478 | PDZ domain |
| Domain | IPR008144 | Guanylate kinase-like domain |
| Domain | IPR008145 | Guanylate kinase/L-type calcium channel beta subunit |
| Domain | IPR019590 | Disks large homologue 1, N-terminal PEST domain |
| Domain | IPR035759 | Disks Large homologue 2, SH3 domain |
| Family | IPR016313 | Disks large 1-like |
| Homologous_superfamily | IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
| Homologous_superfamily | IPR036028 | SH3-like domain superfamily |
| Homologous_superfamily | IPR036034 | PDZ superfamily |
Domain Details Per Protein
Interactions and Pathways
No data available
Plasmids
No data available