ZFIN ID: ZDB-GENE-050208-773
Gene Name: Rho guanine nucleotide exchange factor (GEF) 3
Gene Symbol: arhgef3    Nomenclature History

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Previous Name: si:ch211-258l4.8

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 22 Mapping Details/Browsers
Description: Predicted to have Rho guanyl-nucleotide exchange factor activity. Involved in myeloid cell development. Orthologous to human ARHGEF3 (Rho guanine nucleotide exchange factor 3).
Genome Resources: Alliance (1),  Gene:570228 (1),  Ensembl(GRCz11):ENSDARG00000013834 (2)
GENE EXPRESSION No data available
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa15778 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa43889 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-arhgef3 N/A 1
    DISEASE ASSOCIATED WITH arhgef3 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH arhgef3 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process hemopoiesis (more)
    Molecular Function guanyl-nucleotide exchange factor activity (more)
    GO Terms (all 6)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA arhgef3-201 (1)    Ensembl 1596
    ncRNA arhgef3-002 (1) 792
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM arhgef3 No data available
    MARKER RELATIONSHIPS
    arhgef3 Contained in: [BAC] CH211-258L4 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001082868 (1)
    Genomic GenBank:AL953867 (1) 177575 nt
    Select Tool
    Polypeptide UniProtKB:Q1MT42 (1) 506 aa
    Sequence Information (all 10)
    ORTHOLOGY for arhgef3 ( Chr: 22 )
    CITATIONS (19)