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ZIRC
ZFIN ID: ZDB-GENE-050208-755
Gene Name: YjeF N-terminal domain containing 3
Gene Symbol: yjefn3    Nomenclature History

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Previous Names: aibp2 (1), si:ch211-212d10.3

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 22 Mapping Details/Browsers
Description: Predicted to have NADHX epimerase activity and NADPHX epimerase activity. Involved in several processes, including membrane raft distribution; regulation of cholesterol efflux; and sprouting angiogenesis. Predicted to localize to the mitochondrion. Is expressed in somite. Orthologous to human YJEFN3 (YjeF N-terminal domain containing 3).
Genome Resources: Alliance (1),  Gene:557840 (1),  Ensembl(GRCz11):ENSDARG00000061692 (2)
GENE EXPRESSION
All Expression Data: 2 figures from Fang et al., 2013
Wild-type Stages, Structures: Segmentation:14-19 somites (16.0h-19.0h) to Pharyngula:Prim-25 (36.0h-42.0h)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa24146 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-yjefn3 N/A 1
    MO2-yjefn3 N/A 1
    DISEASE ASSOCIATED WITH yjefn3 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH yjefn3 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process membrane raft distribution (more)
    Cellular Component mitochondrion (more)
    Molecular Function NADHX epimerase activity (more)
    GO Terms (all 7)
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA yjefn3-201 (1)    Ensembl 856
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    Name Type Isotype Host Organism Assay Source Publications
    Ab1-yjefn3 polyclonal Guinea pig 1
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM yjefn3 No data available
    MARKER RELATIONSHIPS
    yjefn3 Contained in: [BAC] CH211-212D10 (1) (order this), DKEY-11N6 (1) (order this)
    yjefn3 Encodes: [EST] IMAGE:7155437 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001044843 (1) 741 bp
    Genomic GenBank:BX664610 (1) 206964 bp Blast at MegaBLAST
    Polypeptide UniProtKB:Q1LVI2 (1) 246 aa
    Sequence Clusters UniGene:89654 (1)
    Sequence Information (all 11)
    ORTHOLOGY for yjefn3 ( Chr: 22 )
    CITATIONS (17)