ZFIN ID: ZDB-GENE-050208-744
Gene Name: one cut homeobox 3a
Gene Symbol: onecut3a    Nomenclature History

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Previous Names: onecut3, si:ch211-195m2.4

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 22 Mapping Details/Browsers
Description: Predicted to have DNA binding activity. Involved in liver development. Predicted to localize to nucleus. Is expressed in intestine and liver. Orthologous to human ONECUT3 (one cut homeobox 3).
Genome Resources: Alliance (1),  Gene:565854 (1),  Ensembl(GRCz11):ENSDARG00000056395 (1)
GENE EXPRESSION
All Expression Data: Fig. 2 from Matthews et al., 2008
Wild-type Stages, Structures: Gastrula:Shield (6.0h-8.0h) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
 
High Throughput Expression: Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa7494 Point Mutation Unknown Missense ENU
sa43821 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-onecut3a N/A 1
    MO2-onecut3a N/A 1
    PHENOTYPE
    Data: Fig. 3 from Matthews et al., 2008
    Observed in:
    DISEASE ASSOCIATED WITH onecut3a HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH onecut3a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process liver development (more)
    Cellular Component nucleus (more)
    Molecular Function DNA binding (more)
    GO Terms (all 5)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA onecut3a-201 (1)    Ensembl 1339
    Browsers: NCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM onecut3a No data available
    MARKER RELATIONSHIPS
    onecut3a Contained in: [BAC] CH211-195M2 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:XM_689117 (1) 1356 nt
    Genomic GenBank:BX088720 (1) 190269 nt
    Select Tool
    Polypeptide UniProtKB:F1QBJ8 (1) 446 aa
    Sequence Information (all 6)
    ORTHOLOGY for onecut3a ( Chr: 22 )
    CITATIONS (19)