ZFIN is now using GRCz12tu for Genomic Data
Gene
rc3h1a
- ID
- ZDB-GENE-050208-702
- Name
- ring finger and CCCH-type domains 1a
- Symbol
- rc3h1a Nomenclature History
- Previous Names
-
- rc3h1
- si:dkey-192m14.4
- Type
- protein_coding_gene
- Location
- Chr: 22 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable RNA binding activity and ubiquitin protein ligase activity. Predicted to be involved in nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; protein polyubiquitination; and ubiquitin-dependent protein catabolic process. Predicted to be located in P-body. Predicted to be active in cytoplasmic stress granule. Orthologous to human RC3H1 (ring finger and CCCH-type domains 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| ?Immune dysregulation and systemic hyperinflammation syndrome | 618998 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR017907 | Zinc finger, RING-type, conserved site |
| Domain | IPR000571 | Zinc finger, CCCH-type |
| Domain | IPR001841 | Zinc finger, RING-type |
| Domain | IPR041523 | Roquin II |
| Domain | IPR048575 | Roquin 1/2-like, ROQ domain |
| Family | IPR052249 | Roquin domain-containing protein |
| Homologous_superfamily | IPR013083 | Zinc finger, RING/FYVE/PHD-type |
| Homologous_superfamily | IPR036855 | Zinc finger, CCCH-type superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Roquin 1/2-like, ROQ domain | Roquin domain-containing protein | Roquin II | Zinc finger, CCCH-type | Zinc finger, CCCH-type superfamily | Zinc finger, RING/FYVE/PHD-type | Zinc finger, RING-type | Zinc finger, RING-type, conserved site |
|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:Q1LV60 | InterPro | 1078 | ||||||||
| UniProtKB:B3DIY0 | InterPro | 1078 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
rc3h1a-201
(1)
|
Ensembl | 3,648 nt | ||
| mRNA |
rc3h1a-202
(1)
|
Ensembl | 3,440 nt | ||
| mRNA |
rc3h1a-203
(1)
|
Ensembl | 3,539 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers