Gene

shc2

ID
ZDB-GENE-050208-666
Name
SHC (Src homology 2 domain containing) transforming protein 2
Symbol
shc2 Nomenclature History
Previous Names
  • si:dkey-94n12.3
  • zgc:162768
Type
protein_coding_gene
Location
Chr: 22 Mapping Details/Browsers
Description
Predicted to have receptor tyrosine kinase binding activity. Predicted to be involved in transmembrane receptor protein tyrosine kinase signaling pathway. Predicted to localize to plasma membrane. Orthologous to human SHC2 (SHC adaptor protein 2).
Genome Resources
Note
None
Expression
All Expression Data
1 figure from Yang et al., 2017
Cross-Species Comparison
High Throughput Data
No data available
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With shc2 Human Ortholog
No data available
Associated With shc2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000980 SH2 domain
Domain IPR006019 Phosphotyrosine interaction domain, Shc-like
Domain IPR006020 PTB/PI domain
Domain IPR035676 SH2 adaptor protein C, SH2 domain
Family IPR029591 SHC-transforming protein 2
Homologous_superfamily IPR011993 PH-like domain superfamily
Homologous_superfamily IPR036860 SH2 domain superfamily
Domain Details Per Protein
Protein Length PH-like domain superfamily Phosphotyrosine interaction domain, Shc-like PTB/PI domain SH2 adaptor protein C, SH2 domain SH2 domain SH2 domain superfamily SHC-transforming protein 2
UniProtKB:A0A0R4IEK8 101
UniProtKB:A3KNZ1 101
UniProtKB:Q1LX18 501
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Gene Tree
Ensembl
Citations