ZFIN ID: ZDB-GENE-050208-570
Gene Name: nischarin
Gene Symbol: nisch    Nomenclature History

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Previous Names: sb:eu276, si:ch1073-288d12.1, si:ch211-103f16.1

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 22 Mapping Details/Browsers
Description: Predicted to have protein kinase binding activity. Predicted to localize to cytoplasm. Is expressed in hindbrain neural plate. Human ortholog(s) of this gene implicated in congestive heart failure. Orthologous to human NISCH (nischarin).
Genome Resources: Alliance (1),  Gene:553087 (1),  Ensembl(GRCz11):ENSDARG00000043077 (2)
GENE EXPRESSION
All Expression Data: 9 figures from 3 publications
Directly Submitted Expression Data: 6 figures (5 images) from Thisse et al., 2004 [IMAGE:7145300]
  1 figure (1 image) from Thisse et al., 2005 [eu276]
  1 figure (1 image) from Thisse et al., 2005 [eu290]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
High Throughput Expression: Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Sequence Targeting Reagents
Targeting Reagent Created Alleles Publications
CRISPR1-nisch
1
CRISPR2-nisch
1
PHENOTYPE No data available
DISEASE ASSOCIATED WITH nisch HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH nisch VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Cellular Component cytoplasm (more)
Molecular Function integrin binding (more)
GO Terms (all 4)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA nisch-202 (1)    Ensembl 4861
ncRNA nisch-002 (1)    Ensembl 1313
Browsers: NCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM nisch No data available
MARKER RELATIONSHIPS
nisch Contained in: [BAC] CH211-103F16 (1)
[Fosmid] CH1073-171C12 (1), CH1073-288D12 (1)
nisch Encodes: [EST] eu276 (1), eu290 (1), IMAGE:7145300 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:XM_002666230 (1) 4907 nt
Genomic GenBank:BX908397 (1) 87359 nt
Select Tool
Polypeptide UniProtKB:A0A2R8Q0B5 (1) 1433 aa
Sequence Information (all 27)
ORTHOLOGY for nisch ( Chr: 22 )
CITATIONS (19)