Gene

lama3

ID
ZDB-GENE-050208-475
Name
laminin, alpha 3
Symbol
lama3 Nomenclature History
Previous Names
  • si:dkey-121a11.10
Type
protein_coding_gene
Location
Chr: 22 Mapping Details/Browsers
Description
Predicted to have signaling receptor binding activity. Predicted to be involved in animal organ morphogenesis; neuron projection development; and tissue development. Predicted to localize to basement membrane. Is expressed in central nervous system; head; integument; and pectoral fin. Human ortholog(s) of this gene implicated in junctional epidermolysis bullosa; junctional epidermolysis bullosa Herlitz type; junctional epidermolysis bullosa non-Herlitz type; and lung small cell carcinoma. Orthologous to human LAMA3 (laminin subunit alpha 3).
Genome Resources
Note
None
Expression
All Expression Data
2 figures from 2 publications
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With lama3 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
junctional epidermolysis bullosa Herlitz type Alliance Epidermolysis bullosa, junctional, Herlitz type 226700
junctional epidermolysis bullosa non-Herlitz type Alliance Epidermolysis bullosa, generalized atrophic benign 226650
Laryngoonychocutaneous syndrome 245660
Associated With lama3 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001791 Laminin G domain
Domain IPR002049 Laminin EGF domain
Domain IPR009254 Laminin alpha, domain I
Domain IPR010307 Laminin domain II
Homologous_superfamily IPR013320 Concanavalin A-like lectin/glucanase domain superfamily
Domain Details Per Protein
Protein Length Concanavalin A-like lectin/glucanase domain superfamily Laminin alpha, domain I Laminin domain II Laminin EGF domain Laminin G domain
UniProtKB:Q1LXE7 1263
UniProtKB:A0A2R8Q7H6 1711
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations