ZFIN ID: ZDB-GENE-050208-411
Gene Name: retinol dehydrogenase 5 (11-cis/9-cis)
Gene Symbol: rdh5    Nomenclature History

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Names: im:6901729, si:dkey-102c8.5

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 22 Mapping Details/Browsers
Description: Predicted to have oxidoreductase activity. Involved in eye photoreceptor cell differentiation; retina development in camera-type eye; and vitamin A biosynthetic process. Predicted to localize to integral component of membrane. Is expressed in several structures, including gut; heart; pineal complex; skeletal muscle cell; and visual system. Human ortholog(s) of this gene implicated in fundus albipunctatus and night blindness. Orthologous to human RDH5 (retinol dehydrogenase 5).
Genome Resources: Alliance (1),  Gene:556528 (1),  Ensembl(GRCz11):ENSDARG00000008306 (2)
GENE EXPRESSION
All Expression Data: 9 figures from 3 publications
Directly Submitted Expression Data: 5 figures (5 images) from Thisse et al., 2004 [IMAGE:6901729]
Wild-type Stages, Structures: Segmentation:14-19 somites (16.0h-19.0h) to Adult (90d-730d, breeding adult)
 
High Throughput Expression: Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa3191 Point Mutation Unknown Premature Stop ENU
sa5966 Point Mutation Unknown Premature Stop ENU
sa37435 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-rdh5 N/A 1
    MO2-rdh5 N/A 1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH rdh5 HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    fundus albipunctatus Alliance Fundus albipunctatus 136880
    DISEASE ASSOCIATED WITH rdh5 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process vitamin A biosynthetic process (more)
    Cellular Component integral component of membrane (more)
    Molecular Function oxidoreductase activity (more)
    GO Terms (all 6)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA rdh5-202 (1)    Ensembl 1321
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM rdh5 No data available
    MARKER RELATIONSHIPS
    rdh5 Contained in: [BAC] DKEY-102C8 (1) (order this)
    rdh5 Encodes: [EST] IMAGE:6901729 (1)
    [cDNA] MGC:114091 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001030101 (1) 1626 nt
    Genomic GenBank:BX324213 (1) 94824 nt
    Select Tool
    Polypeptide UniProtKB:Q1LXG1 (1) 344 aa
    Sequence Information (all 19)
    ORTHOLOGY for rdh5 ( Chr: 22 )
    CITATIONS (23)