Gene
bglap
- ID
- ZDB-GENE-050113-4
- Name
- bone gamma-carboxyglutamate (gla) protein
- Symbol
- bglap Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Description
- Predicted to have calcium ion binding activity and hydroxyapatite binding activity. Involved in response to mechanical stimulus. Predicted to localize to extracellular region. Is expressed in several structures, including osteoblast; renal tubule; scale; skeletal system; and trabecular layer. Human ortholog(s) of this gene implicated in osteoarthritis; osteoporosis; prostate cancer; rheumatoid arthritis; and vitamin K deficiency bleeding. Orthologous to human BGLAP (bone gamma-carboxyglutamate protein).
- Genome Resources
- Note
- None
- Comparative Information
- All Expression Data
- 42 figures from 33 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
Protein | Length | Gamma-carboxyglutamic acid-rich (GLA) domain | Gamma-carboxyglutamic acid-rich (GLA) domain superfamily | Osteocalcin |
---|---|---|---|---|
UniProtKB:Q4G6A6
|
104 |
Interactions and Pathways
No data available
Plasmids
No data available