ZFIN ID: ZDB-GENE-041212-53
Gene Name: PTEN induced kinase 1
Gene Symbol: pink1
Sequence Ontology ID : SO:0000704

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Names: wu:fc39e12, zgc:101729 (1)

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Location: Chr: 23 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have protein serine/threonine kinase activity; involved in several processes, including animal organ development, autophagy of mitochondrion, and dopaminergic neuron differentiation;  ...
GENE EXPRESSION
All Expression Data: 18 figures from 9 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:101729]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
gi2 Small Deletion Unknown Premature Stop TALEN
ihb272 Insertion Exon 2 Unknown CRISPR
ihb273 Small Deletion Exon 2 Unknown CRISPR
sh397 Point Mutation Unknown Unknown ENU
zf1035 Small Deletion Unknown Unknown CRISPR
Targeting reagents:
PHENOTYPE
Data: 31 figures from 10 publications
Observed in:
DISEASE ASSOCIATED WITH pink1 HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
autosomal recessive early-onset Parkinson's disease 6 Parkinson disease 6, early onset 605909
GENE ONTOLOGY
Ontology GO Term
Biological Process autophagy of mitochondrion (more)
Cellular Component cytosol (more)
Molecular Function ATP binding (more)
GO Terms (all 19)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000719 (1)
  • InterPro:IPR008271 (1)
  • InterPro:IPR011009 (1)
  • InterPro:IPR040110 (1)
  • PROSITE:PS00108 (1)
  • PROSITE:PS50011 (1)
  • Pfam:PF00069 (1)
  • TRANSCRIPTS No data available
    GENE PRODUCT DESCRIPTION No description available
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM pink1
    MARKER RELATIONSHIPS
    pink1Encodes: [EST] fc39e12
    [cDNA] MGC:101729 (1) (order this), MGC:175012 (1) (order this), MGC:192855 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001008628 (1) 2088bp
    Polypeptide UniProtKB:B5DFT6 (1) 574aa
    Sequence Clusters UniGene:78644 (1)
    Sequence Information (all 21)
    OTHER pink1 GENE PAGES
  • Alliance (1)
  • Gene:494085 (1)
  • Ensembl(GRCz11):ENSDARG00000001929 (2)
  • ORTHOLOGY for pink1 (Chr: 23)
    CITATIONS (39)