Gene

kera

ID
ZDB-GENE-041210-165
Name
keratocan
Symbol
kera Nomenclature History
Previous Names
  • si:dkeyp-38g8.3
  • zgc:136259
Type
protein_coding_gene
Location
Chr: 4 Mapping Details/Browsers
Description
Predicted to be involved in response to stimulus and visual perception. Predicted to localize to extracellular space. Is expressed in central nervous system; corneal epithelial cell; epidermis; and eye. Human ortholog(s) of this gene implicated in arcus senilis; cornea plana; and corneal dystrophy. Orthologous to human KERA (keratocan).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
12 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Yeh et al., 2008
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With kera Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
cornea plana Alliance Cornea plana 2, autosomal recessive 217300
Associated With kera Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000372 Leucine-rich repeat N-terminal domain
Homologous_superfamily IPR032675 Leucine-rich repeat domain superfamily
Repeat IPR001611 Leucine-rich repeat
Repeat IPR003591 Leucine-rich repeat, typical subtype
Domain Details Per Protein
Protein Length Leucine-rich repeat Leucine-rich repeat domain superfamily Leucine-rich repeat N-terminal domain Leucine-rich repeat, typical subtype
UniProtKB:Q5RI47 156
UniProtKB:Q5RI43 348
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-kera Rabbit
  • IHC
  • WB
1
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations