Gene
ace2
- ID
- ZDB-GENE-041114-6
- Name
- angiotensin I converting enzyme 2
- Symbol
- ace2 Nomenclature History
- Previous Names
-
- zgc:92514 (1)
- Type
- protein_coding_gene
- Location
- Chr: 11 Mapping Details/Browsers
- Description
- Predicted to enable carboxypeptidase activity and metallopeptidase activity. Predicted to be involved in angiotensin maturation. Predicted to act upstream of or within proteolysis. Predicted to be located in several cellular components, including apical plasma membrane; cilium; and extracellular region. Predicted to be active in extracellular space and plasma membrane. Is expressed in brain; gill; heart; liver; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in several diseases, including avian influenza; cerebral malaria; hypertension (multiple); respiratory syncytial virus infectious disease; and severe acute respiratory syndrome. Orthologous to human ACE2 (angiotensin converting enzyme 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 4 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Collectrin domain | Peptidase M2, peptidyl-dipeptidase A |
|---|---|---|---|---|
| UniProtKB:A0A8M2BGN5 | InterPro | 807 | ||
| UniProtKB:E7F9E5 | InterPro | 818 | ||
| UniProtKB:Q5U380 | InterPro | 785 | ||
| UniProtKB:A0AB32TXH6 | InterPro | 783 |
Interactions and Pathways
No data available
Plasmids
No data available