ZFIN ID: ZDB-GENE-041114-57
Gene Name: solute carrier family 6 member 1b
Gene Symbol: slc6a1b    Nomenclature History

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Previous Names: gat-1 (1), slc6a1, wu:fj45h10, wu:fq41d04, zgc:103663

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 11 Mapping Details/Browsers
Description: Predicted to have gamma-aminobutyric acid:sodium symporter activity and neurotransmitter binding activity. Predicted to be involved in neurotransmitter transport. Predicted to localize to the axon; cell surface; and plasma membrane. Is expressed in basal plate midbrain region and nervous system. Orthologous to human SLC6A1 (solute carrier family 6 member 1).
Genome Resources: Alliance (1),  Gene:492490 (1),  Ensembl(GRCz11):ENSDARG00000039647 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa27704 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa41754 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH slc6a1b HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    Myoclonic-atonic epilepsy 616421
    DISEASE ASSOCIATED WITH slc6a1b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process neurotransmitter transport (more)
    Cellular Component integral component of membrane (more)
    Molecular Function gamma-aminobutyric acid:sodium symporter activity (more)
    GO Terms (all 13)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Family IPR000175 Sodium:neurotransmitter symporter
    Family IPR002980 Sodium:neurotransmitter symporter, GABA, GAT-1
    Homologous_superfamily IPR037272 Sodium:neurotransmitter symporter superfamily
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA slc6a1b-201 (1)    Ensembl 3993
    ncRNA slc6a1b-002 (1)    Ensembl 645
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM slc6a1b No data available
    MARKER RELATIONSHIPS
    slc6a1b Contained in: [Fosmid] CH1073-274B24 (1), CH1073-280O20 (1)
    slc6a1b Encodes: [EST] fj45h10, fq41d04 (1) (order this)
    [cDNA] MGC:103663 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001007362 (1) 2307 bp
    Genomic GenBank:CU855911 (1) 35004 bp
    Select Tool
    Polypeptide UniProtKB:Q5U3E5 (1) 600 aa
    Sequence Information (all 16)
    ORTHOLOGY for slc6a1b ( Chr: 11 )
    CITATIONS (31)