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ZIRC
ZFIN ID: ZDB-GENE-041114-207
Gene Name: Cbl proto-oncogene, E3 ubiquitin protein ligase
Gene Symbol: cbl
Sequence Ontology ID : SO:0001217

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Previous Names: wu:fd16a12, zgc:92560 (1)

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(Including Attributions)
Location: Chr: 15 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have SH3 domain binding activity; receptor tyrosine kinase binding activity; and ubiquitin protein ligase activity. Involved in definitive hemopoiesis. Predicted to localize to the  ...
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:92560]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
Curated Microarray Expression: GEO (1)
DISEASE ASSOCIATED WITH cbl HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
juvenile myelomonocytic leukemia ?Juvenile myelomonocytic leukemia 607785
Noonan syndrome-like disorder with or without juvenile myelomonocytic leukemia 613563
DISEASE ASSOCIATED WITH cbl VIA EXPERIMENTAL MODELS
Human Disease Fish Conditions Citations
myeloproliferative neoplasm cblrj32/rj32(TU) standard conditions Peng et al., 2015
GENE ONTOLOGY
Ontology GO Term
Biological Process definitive hemopoiesis (more)
Cellular Component membrane raft (more)
Molecular Function calcium ion binding (more)
GO Terms (all 14)
TRANSCRIPTS
Type Name Length (bp) Analysis
mRNA cbl-201 (1) 4069
GENE PRODUCT DESCRIPTION No description available
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM cbl No data available
MARKER RELATIONSHIPS
cbl Contained in: [BAC] DKEY-257C10 (1) (order this)
cbl Encodes: [EST] fd16a12
[cDNA] MGC:92560 (1) (order this)
SEQUENCE INFORMATION
Type Accession # Length (bp/aa) Analysis
RNA RefSeq:NM_001007330 (1) 4023 bp
Genomic GenBank:BX571886 (1) 178049 bp
Select Tool
Polypeptide UniProtKB:F1QI90 (1) 913 aa
Sequence Clusters UniGene:78552 (1)
Sequence Information (all 14)
ORTHOLOGY for cbl ( Chr: 15 )
CITATIONS (27)