ZFIN ID: ZDB-GENE-041111-294
Gene Name: malic enzyme 3, NADP(+)-dependent, mitochondrial
Gene Symbol: me3    Nomenclature History

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Previous Names: im:7151680, wu:fi43b04, zgc:163117 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 9 Mapping Details/Browsers
Description: Predicted to have malate dehydrogenase (decarboxylating) (NADP+) activity. Predicted to be involved in malate metabolic process and pyruvate metabolic process. Predicted to localize to mitochondrion. Is expressed in pectoral fin musculature and pronephric duct. Orthologous to several human genes including ME3 (malic enzyme 3).
Genome Resources: Alliance (1),  Gene:492719 (1),  Ensembl(GRCz11):ENSDARG00000002305 (2)
GENE EXPRESSION
All Expression Data: 7 figures from 2 publications
Directly Submitted Expression Data: 6 figures (5 images) from Thisse et al., 2004 [IMAGE:7151680]
Wild-type Stages, Structures: Gastrula:50%-epiboly (5.25h-5.66h) to Hatching:Long-pec (48.0h-60.0h)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa1196 Point Mutation Unknown Splice Site ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH me3 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH me3 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process oxidation-reduction process (more)
    Cellular Component mitochondrion (more)
    Molecular Function malate dehydrogenase (decarboxylating) (NAD+) activity (more)
    GO Terms (all 10)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA me3-201 (1)    Ensembl 2829
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM me3 No data available
    MARKER RELATIONSHIPS
    me3 Contained in: [BAC] CH211-218D20 (1)
    me3 Encodes: [EST] fi43b04, IMAGE:7151680 (1)
    [cDNA] MGC:163117 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001089356 (1) 2826 nt
    Genomic GenBank:BX294189 (1) 194025 nt
    Select Tool
    Polypeptide UniProtKB:A4QPA0 (1) 603 aa
    Sequence Information (all 14)
    ORTHOLOGY for me3 ( Chr: 9 )
    CITATIONS (26)