ZFIN ID: ZDB-GENE-041111-162
Gene Name: GLI family zinc finger 3
Gene Symbol: gli3

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Name: im:7142603

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Location: Chr: 24 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 15 figures from 13 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [IMAGE:7142603]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
  brain, central nervous system, ceratohyal cartilage perichondrium, diencephalon (all 23) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
hu2162 Point Mutation Unknown Unknown ENU
hu2965 Point Mutation Unknown Premature Stop ENU
hu2966 Point Mutation Unknown Unknown ENU
la011615Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la014494Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la014495Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa8416 Point Mutation Unknown Premature Stop ENU
    sa8870 Point Mutation Unknown Premature Stop ENU
    sa25210 Point Mutation Unknown Premature Stop ENU
    sa32478 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa37837 Point Mutation Unknown Premature Stop ENU
    sa37838 Point Mutation Unknown Premature Stop ENU
    Targeting reagents: MO1-gli3 (1), MO2-gli3 (1)
    PHENOTYPE
    Data: Fig. 5 from Devine et al., 2009
    Observed in: adenohypophysis morphogenesis, spinal cord, spinal cord dorsal/ventral patterning
    DISEASE ASSOCIATED WITH gli3 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    Greig cephalopolysyndactyly syndrome Greig cephalopolysyndactyly syndrome 175700
    Pallister-Hall syndrome Pallister-Hall syndrome 146510
    polydactyly Polydactyly, postaxial, types A1 and B 174200
    Polydactyly, preaxial, type IV 174700
    {Hypothalamic hamartomas, somatic} 241800
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process generation of neurons (more)
    Molecular Function DNA binding (more)
    GO Terms (all 10)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR007087 (1)
  • InterPro:IPR013087 (1)
  • InterPro:IPR015880 (1)
  • InterPro:IPR032851 (1)
  • PROSITE:PS00028 (1)
  • PROSITE:PS50157 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA gli3-001 (1) 6688
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    SignaFish
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM gli3 No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    gli3Contained in: [BAC] CH73-105F15 (1) (order this), CH211-281G2 (1) (order this), DKEY-90P8 (1) (order this), DKEY-149L16 (1) (order this)
    [Fosmid] CH1073-45O15 (1) (order this), CH1073-328K10 (1) (order this)
    gli3Encodes: [EST] IMAGE:7142603 (1) (order this)
    [cDNA] MGC:194808 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_205728 (1) 5086bp
    Genomic GenBank:BX005153 (1) 177146bp
    Select Tool
    Polypeptide UniProtKB:F1QSH8 (1) 1553aa
    Sequence Clusters UniGene:99315 (1)
    Sequence Information (all 21)
    OTHER gli3 GENE PAGES
  • Gene:403042 (1)
  • VEGA:OTTDARG00000018205 (1)
  • Ensembl(GRCz10):ENSDARG00000052131 (1)
  • ORTHOLOGY for gli3 (Chr: 24)
    CITATIONS (42)