ZFIN Gene: col5a1

ZFIN ID: ZDB-GENE-041105-6

ZFIN ID: ZDB-GENE-041105-6

Gene Name:

procollagen, type V, alpha 1

Gene Symbol:

col5a1

Sequence Ontology ID :

SO:0001217

Previous Name:

si:dkey-87m23.1

Location:

Chr: 21 Mapping Details/Browsers

Nomenclature History

AUTOMATED DESCRIPTION

Predicted to have extracellular matrix structural constituent and heparin binding activity. Predicted to be involved in cell adhesion and collagen fibril organization. Predicted to localize to the ...

GENE EXPRESSION
All Expression Data:	14 figures from 5 publications
Wild-type Stages, Structures:	Cleavage:8-cell (1.25h-1.5h) to Adult (90d-730d, breeding adult)
	ceratohyal cartilage cranial cartilage cranial neural crest dermis eye mesenchymal cell hindbrain Meckel's cartilage myotome neural crest neurocranial trabecula notochord posterior side notochord otic vesicle parachordal cartilage pharyngeal arch 2 somite trabecula cranii whole organism
Curated Microarray Expression:	GEO (1)

MUTATIONS AND SEQUENCE TARGETING REAGENTS

Allele	Type	Localization	Consequence	Mutagen	Suppliers
la028380Tg	Transgenic Insertion	Unknown	Unknown	DNA	Zebrafish International Resource Center (ZIRC) (order this)
sa4934	Point Mutation	Unknown	Splice Site	ENU
sa5957	Point Mutation	Unknown	Splice Site	ENU
sa23852	Point Mutation	Unknown	Splice Site	ENU	European Zebrafish Resource Center (EZRC) (order this) Zebrafish International Resource Center (ZIRC) (order this)
sa37227	Point Mutation	Unknown	Premature Stop	ENU	European Zebrafish Resource Center (EZRC) (order this) Zebrafish International Resource Center (ZIRC) (order this)
sa37228	Point Mutation	Unknown	Premature Stop	ENU	European Zebrafish Resource Center (EZRC) (order this) Zebrafish International Resource Center (ZIRC) (order this)
sa43580	Point Mutation	Unknown	Splice Site	ENU	European Zebrafish Resource Center (EZRC) (order this) Zebrafish International Resource Center (ZIRC) (order this)
sa45726	Point Mutation	Unknown	Splice Site	ENU	Zebrafish International Resource Center (ZIRC) (order this)

Targeting reagents:

PHENOTYPE No data available

DISEASE ASSOCIATED WITH col5a1 HUMAN ORTHOLOG

Disease Ontology Term	OMIM Term	OMIM Phenotype ID
type I Ehlers-Danlos syndrome	Ehlers-Danlos syndrome, classic type, 1	130000

DISEASE ASSOCIATED WITH col5a1 VIA EXPERIMENTAL MODELS No data available

GENE ONTOLOGY

Ontology	GO Term
Biological Process	cell adhesion (more)
Cellular Component	collagen trimer (more)
Molecular Function	extracellular matrix structural constituent (more)

GO Terms (all 9)

PROTEIN FAMILIES, DOMAINS AND SITES
InterPro:IPR000885 (1) InterPro:IPR001791 (1) InterPro:IPR008160 (1) InterPro:IPR013320 (1)	PROSITE:PS51461 (1)	Pfam:PF01391 (1) Pfam:PF01410 (1) Pfam:PF02210 (1)

TRANSCRIPTS
Type	Name	Length (bp)	Analysis
mRNA	col5a1-201 (1)	9581	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

GENE PRODUCT DESCRIPTION No description available

INTERACTIONS AND PATHWAYS

ANTIBODIES No data available

PLASMIDS No data available

CONSTRUCTS WITH SEQUENCES FROM col5a1 No data available

MARKER RELATIONSHIPS

col5a1 Contained in:	[BAC] CH73-165E7 (1) (order this), CH73-331J9 (1) (order this), DKEY-87M23 (1) (order this) [Fosmid] CH1073-153C9 (1) (order this)
col5a1 Has Artifact:	[EST] fc69d06

SEQUENCE INFORMATION

Type	Accession #	Length (bp/aa)	Analysis
RNA	RefSeq:XM_021468998 (1)		Select Tool ZFIN BLAST NCBI BLAST MegaBLAST Ensembl UCSC BLAT
Genomic	GenBank:FP102894 (1)	92532 bp	Select Tool MegaBLAST Ensembl
Polypeptide	UniProtKB:F6NPA4 (1)	2011 aa	Select Tool ZFIN BLAST SIB BLAST Ensembl Protein Blast
Sequence Clusters	UniGene:105938 (1)

Sequence Information (all 34)

OTHER col5a1 GENE PAGES

Alliance (1)

Gene:100334431 (1)

VEGA:OTTDARG00000028977 (1)

Ensembl(GRCz11):ENSDARG00000012593 (2)

ORTHOLOGY for col5a1 ( Chr: 21 )

CITATIONS (33)

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