Gene

myo3a

ID
ZDB-GENE-041026-4
Name
myosin IIIA
Symbol
myo3a Nomenclature History
Previous Names
None
Type
protein_coding_gene
Location
Chr: 24 Mapping Details/Browsers
Description
Predicted to have several functions, including ATP binding activity; actin binding activity; and motor activity. Predicted to be involved in protein phosphorylation; response to stimulus; and visual perception. Predicted to localize to myosin complex. Is expressed in axis; notochord; photoreceptor inner segment layer; polster; and retina. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 30. Orthologous to human MYO3A (myosin IIIA).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
8 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With myo3a Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
autosomal recessive nonsyndromic deafness 30 Alliance Deafness, autosomal recessive 30 607101
Associated With myo3a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Binding_site IPR000048 IQ motif, EF-hand binding site
Binding_site IPR017441 Protein kinase, ATP binding site
Domain IPR000719 Protein kinase domain
Domain IPR001609 Myosin head, motor domain
Domain IPR036083 Class III myosin, motor domain
Homologous_superfamily IPR011009 Protein kinase-like domain superfamily
Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
Homologous_superfamily IPR036961 Kinesin motor domain superfamily
Domain Details Per Protein
Protein Length Class III myosin, motor domain IQ motif, EF-hand binding site Kinesin motor domain superfamily Myosin head, motor domain P-loop containing nucleoside triphosphate hydrolase Protein kinase, ATP binding site Protein kinase domain Protein kinase-like domain superfamily
UniProtKB:F1QDH9 1749
UniProtKB:A0A286YBM4 1761
UniProtKB:F1RAJ1 1775
UniProtKB:Q90XG6 1775
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-myo3a polyclonal Rabbit
  • IHC
  • WB
1
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations