Gene

atf6

ID
ZDB-GENE-041014-328
Name
activating transcription factor 6
Symbol
atf6 Nomenclature History
Previous Names
  • fi12h10
  • si:ch211-199m3.9
  • si:ch211-260g14.1
  • wu:fi12h10
Type
protein_coding_gene
Location
Chr: 20 Mapping Details/Browsers
Description
Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in endoplasmic reticulum unfolded protein response and response to hypoxia. Predicted to localize to nucleus. Is expressed in brain; head; liver; and trunk. Human ortholog(s) of this gene implicated in achromatopsia 7. Orthologous to human ATF6 (activating transcription factor 6).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
23 figures from 19 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Cinaroglu et al., 2011
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With atf6 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
achromatopsia 7 Alliance Achromatopsia 7 616517
Associated With atf6 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR004827 Basic-leucine zipper domain
Family IPR029801 cAMP-dependent transcription factor ATF-6 alpha
Domain Details Per Protein
Protein Length Basic-leucine zipper domain cAMP-dependent transcription factor ATF-6 alpha
UniProtKB:Q5RH85 653
UniProtKB:U3JA59 284
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations