Gene
atf6
- ID
- ZDB-GENE-041014-328
- Name
- activating transcription factor 6
- Symbol
- atf6 Nomenclature History
- Previous Names
-
- fi12h10
- si:ch211-199m3.9
- si:ch211-260g14.1
- wu:fi12h10
- Type
- protein_coding_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Description
- Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in endoplasmic reticulum unfolded protein response and response to hypoxia. Predicted to localize to nucleus. Is expressed in brain; head; liver; and trunk. Human ortholog(s) of this gene implicated in achromatopsia 7. Orthologous to human ATF6 (activating transcription factor 6).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 23 figures from 19 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Cinaroglu et al., 2011
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| achromatopsia 7 | Alliance | Achromatopsia 7 | 616517 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Basic-leucine zipper domain | cAMP-dependent transcription factor ATF-6 alpha |
|---|---|---|---|
|
UniProtKB:Q5RH85
|
653 | ||
|
UniProtKB:U3JA59
|
284 |
Interactions and Pathways
No data available
Plasmids
No data available