Gene
atf6
- ID
- ZDB-GENE-041014-328
- Name
- activating transcription factor 6
- Symbol
- atf6 Nomenclature History
- Previous Names
-
- fi12h10
- si:ch211-199m3.9
- si:ch211-260g14.1
- wu:fi12h10
- Type
- protein_coding_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Description
- Predicted to have DNA-binding transcription factor activity and cAMP response element binding activity. Involved in endoplasmic reticulum unfolded protein response and response to hypoxia. Predicted to localize to endoplasmic reticulum membrane and nucleus. Is expressed in brain; head; liver; and trunk. Human ortholog(s) of this gene implicated in achromatopsia 7. Orthologous to human ATF6 (activating transcription factor 6).
- Genome Resources
- Note
- None
- All Expression Data
- 20 figures from 18 publications
- Cross-Species Comparison
- High Throughput Data
Wild Type Expression Summary
- All Phenotype Data
- Fig. 6 from Cinaroglu et al., 2011
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| achromatopsia 7 | Alliance | Achromatopsia 7 | 616517 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Basic-leucine zipper domain | cAMP-dependent transcription factor ATF-6 alpha |
|---|---|---|---|
|
UniProtKB:Q5RH85
|
653 | ||
|
UniProtKB:U3JA59
|
284 |
Interactions and Pathways
No data available
Plasmids
No data available