Community Action Needed: Please respond to the NIH RFI
Gene

sele

ID
ZDB-GENE-041014-221
Name
selectin E
Symbol
sele Nomenclature History
Previous Names
  • si:ch211-260g14.8 (1)
Type
protein_coding_gene
Location
Chr: 20 Mapping Details/Browsers
Description
Predicted to enable oligosaccharide binding activity and sialic acid binding activity. Predicted to be involved in heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules; leukocyte tethering or rolling; and response to cytokine. Predicted to act upstream of or within cell adhesion. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. Predicted to be active in external side of plasma membrane and extracellular space. Is expressed in intermediate cell mass of mesoderm; posterior cardinal vein; and trunk. Human ortholog(s) of this gene implicated in IgA glomerulonephritis; brain ischemia; cerebrovascular disease; and coronary artery disease. Orthologous to human SELE (selectin E).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
3 figures from Sun et al., 2015
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With sele Human Ortholog
No data available
Associated With sele Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR018378 C-type lectin, conserved site
Domain IPR000436 Sushi/SCR/CCP domain
Domain IPR000742 EGF-like domain
Domain IPR001304 C-type lectin-like
Domain IPR033991 Selectin, C-type lectin-like domain
Family IPR002396 Selectin superfamily
Homologous_superfamily IPR016186 C-type lectin-like/link domain superfamily
Homologous_superfamily IPR016187 C-type lectin fold
Homologous_superfamily IPR035976 Sushi/SCR/CCP superfamily
Domain Details Per Protein
Protein Length C-type lectin, conserved site C-type lectin fold C-type lectin-like C-type lectin-like/link domain superfamily EGF-like domain Selectin, C-type lectin-like domain Selectin superfamily Sushi/SCR/CCP domain Sushi/SCR/CCP superfamily
UniProtKB:F1QTG4 783
UniProtKB:F1QIT5 813
UniProtKB:A0A1L1VU85 871
UniProtKB:B3DLK5 835
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations