Gene

mep1ba

ID

ZDB-GENE-041014-209

Name

meprin A subunit beta a

Symbol

mep1ba Nomenclature History

Previous Names

mep1b
si:ch211-191a24.6 (1)
zgc:153272 (1)

Type

protein_coding_gene

Location

Chr: 20 Mapping Details/Browsers

Description

Predicted to enable metalloendopeptidase activity. Predicted to act upstream of or within proteolysis. Predicted to be located in membrane. Predicted to be active in extracellular space. Is expressed in several structures, including epidermis; gill; heart; liver; and pleuroperitoneal region. Orthologous to human MEP1B (meprin A subunit beta).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

3 figures from 3 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 2 figures from Schütte et al., 2010
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With mep1ba Human Ortholog

No data available

Associated With mep1ba Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000998	MAM domain
Domain	IPR001506	Peptidase M12A
Domain	IPR002083	MATH/TRAF domain
Domain	IPR006026	Peptidase, metallopeptidase
Domain	IPR034038	Meprin peptidase domain
Family	IPR008294	Meprin alpha/beta subunit
Homologous_superfamily	IPR008974	TRAF-like
Homologous_superfamily	IPR013320	Concanavalin A-like lectin/glucanase domain superfamily
Homologous_superfamily	IPR024079	Metallopeptidase, catalytic domain superfamily