ZFIN ID: ZDB-GENE-041014-2
Gene Name: hepatocyte growth factor a
Gene Symbol: hgfa    Nomenclature History

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Names: hgf1, si:dkey-146j3.2

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 4 Mapping Details/Browsers
Description: Predicted to have serine-type endopeptidase activity. Involved in cerebellar granule cell differentiation and neuron migration. Is expressed in several structures, including DEL; adaxial cell; axis; endodermal cell; and forebrain neural rod. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); autosomal recessive nonsyndromic deafness 39; eye disease (multiple); neuropathy (multiple); and scleroderma (multiple). Orthologous to human HGF (hepatocyte growth factor).
Genome Resources: Alliance (1),  Gene:493781 (1),  Ensembl(GRCz11):ENSDARG00000045544 (2)
PHENOTYPE No data available
DISEASE ASSOCIATED WITH hgfa HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
autosomal recessive nonsyndromic deafness 39 Alliance Deafness, autosomal recessive 39 608265
DISEASE ASSOCIATED WITH hgfa VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process central nervous system neuron differentiation (more)
Molecular Function growth factor activity (more)
GO Terms (all 8)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA hgfa-202 (1)    Ensembl 2249
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
SignaFish
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM hgfa No data available
MARKER RELATIONSHIPS
hgfa Contained in: [BAC] DKEY-146J3 (1) (order this)
hgfa Encodes: [EST] IMAGE:7144651 (1)
[cDNA] MGC:162497 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_001013274 (1) 2249 nt
Genomic GenBank:BX897731 (1) 99029 nt
Select Tool
Polypeptide UniProtKB:A4IGA7 (1) 712 aa
Sequence Information (all 17)
ORTHOLOGY for hgfa ( Chr: 4 )
CITATIONS (28)