ZFIN ID: ZDB-GENE-041014-2
Gene Name: hepatocyte growth factor a
Gene Symbol: hgfa
Sequence Ontology ID : SO:0000704

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Previous Names: hgf1, si:dkey-146j3.2

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(Including Attributions)
Location: Chr: 4 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have serine-type endopeptidase activity; involved in cerebellar granule cell differentiation and neuron migration; orthologous to human HGF (hepatocyte growth factor).
GENE EXPRESSION
All Expression Data: 6 figures from 4 publications
Wild-type Stages, Structures: Gastrula:Shield (6.0h-8.0h) to Larval:Protruding-mouth (72.0h-96.0h, 3.5mm)
 
PHENOTYPE No data available
DISEASE ASSOCIATED WITH hgfa HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
autosomal recessive nonsyndromic deafness 39 Deafness, autosomal recessive 39 608265
DISEASE ASSOCIATED WITH hgfa VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process central nervous system neuron differentiation (more)
Cellular Component extracellular space (more)
Molecular Function growth factor activity (more)
GO Terms (all 12)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000001 (1)
  • InterPro:IPR001254 (1)
  • InterPro:IPR001314 (1)
  • InterPro:IPR003609 (1)
  • InterPro:IPR009003 (1)
  • InterPro:IPR013806 (1)
  • InterPro:IPR018056 (1)
  • InterPro:IPR024174 (1)
  • InterPro:IPR027284 (1)
  • InterPro:IPR038178 (1)
  • PROSITE:PS00021 (1)
  • PROSITE:PS50070 (1)
  • PROSITE:PS50240 (1)
  • PROSITE:PS50948 (1)
  • Pfam:PF00024 (1)
  • Pfam:PF00051 (1)
  • Pfam:PF00089 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA hgfa-202 (1) 2249
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    SignaFish
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM hgfa No data available
    MARKER RELATIONSHIPS
    hgfaContained in: [BAC] DKEY-146J3 (1) (order this)
    hgfaEncodes: [EST] IMAGE:7144651 (1) (order this)
    [cDNA] MGC:162497 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001013274 (1) 2249bp
    Genomic GenBank:BX897731 (1) 99029bp
    Select Tool
    Polypeptide UniProtKB:A4IGA7 (1) 712aa
    Sequence Clusters UniGene:91265 (1)
    Sequence Information (all 18)
    OTHER hgfa GENE PAGES
  • Alliance (1)
  • Gene:493781 (1)
  • VEGA:OTTDARG00000008978 (1)
  • Ensembl(GRCz11):ENSDARG00000045544 (2)
  • ORTHOLOGY for hgfa (Chr: 4)
    CITATIONS (25)