ZFIN ID: ZDB-GENE-041010-42
Gene Name: H2A.X variant histone family member 1
Gene Symbol: h2ax1    Nomenclature History

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Previous Names: h2afx1, zgc:101846 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 10 Mapping Details/Browsers
Description: Predicted to have DNA binding activity. Predicted to be involved in chromatin silencing; defense response to other organism; and membrane disruption in other organism. Predicted to localize to extracellular space and nuclear chromatin. Orthologous to several human genes including H2AC21 (H2A clustered histone 21).
Genome Resources: Alliance (1),  Gene:449794 (1),  Ensembl(GRCz11):ENSDARG00000068995 (1)
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:101846]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS No data available
PHENOTYPE No data available
DISEASE ASSOCIATED WITH h2ax1 HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH h2ax1 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process defense response to Gram-positive bacterium (more)
Cellular Component extracellular space (more)
Molecular Function DNA binding (more)
GO Terms (all 12)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA h2afx1-201 (1)    Ensembl 909
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM h2ax1 No data available
MARKER RELATIONSHIPS
h2ax1 Contained in: [BAC] RP71-56I13 (1)
h2ax1 Encodes: [cDNA] MGC:101846 (1), MGC:191402 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_001005967 (1) 919 nt
Genomic GenBank:BX120005 (1) 129782 nt
Select Tool
Polypeptide UniProtKB:Q5XJK2 (1) 128 aa
Sequence Information (all 13)
ORTHOLOGY for h2ax1 ( Chr: 10 )
CITATIONS (19)