Gene

brd1a

ID

ZDB-GENE-041008-168

Name

bromodomain containing 1a

Symbol

brd1a Nomenclature History

Previous Names

brd1
im:7138929
si:dkey-164m14.6 (1)

Type

protein_coding_gene

Location

Chr: 4 Mapping Details/Browsers

Description

Predicted to have metal ion binding activity. Human ortholog(s) of this gene implicated in bipolar disorder and schizophrenia. Orthologous to human BRD1 (bromodomain containing 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:7138929 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With brd1a Human Ortholog

No data available

Associated With brd1a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR019786	Zinc finger, PHD-type, conserved site
Domain	IPR000313	PWWP domain
Domain	IPR001487	Bromodomain
Domain	IPR001965	Zinc finger, PHD-type
Domain	IPR019542	Enhancer of polycomb-like, N-terminal
Domain	IPR019787	Zinc finger, PHD-finger
Domain	IPR034732	Extended PHD (ePHD) domain
Domain	IPR042009	BRPF2, PHD domain
Family	IPR050701	Histone Modification Regulator
Homologous_superfamily	IPR011011	Zinc finger, FYVE/PHD-type
Homologous_superfamily	IPR013083	Zinc finger, RING/FYVE/PHD-type
Homologous_superfamily	IPR036427	Bromodomain-like superfamily

Domain Details Per Protein

Protein	Length	Bromodomain	Bromodomain-like superfamily	BRPF2, PHD domain	Enhancer of polycomb-like, N-terminal	Extended PHD (ePHD) domain	Histone Modification Regulator	PWWP domain	Zinc finger, FYVE/PHD-type	Zinc finger, PHD-finger	Zinc finger, PHD-type	Zinc finger, PHD-type, conserved site	Zinc finger, RING/FYVE/PHD-type
UniProtKB:A0A8M9PHX1 InterPro	949
UniProtKB:A0A8M9Q6D7 InterPro	1141
UniProtKB:F1QFR1 InterPro	1142

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Has Havana Data	Length (nt)	Analysis
mRNA	brd1a-201 (1) Ensembl	Ensembl		6,464 nt	Select Tool ZFIN BLAST
mRNA	brd1a-202 (1) Ensembl	Ensembl		4,208 nt	Select Tool

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations