ZFIN ID: ZDB-GENE-041001-175
Gene Name: nuclear receptor coactivator 1
Gene Symbol: ncoa1    Nomenclature History

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Previous Names: DKEY-34F16.7 (1), si:dkey-34f16.6, si:dkey-5g7.1, si:dkey-5g7.6, SRC1 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 20 Mapping Details/Browsers
Description: Predicted to have nuclear receptor binding activity and nuclear receptor transcription coactivator activity. Predicted to be involved in cellular response to hormone stimulus and positive regulation of transcription by RNA polymerase II. Predicted to localize to nucleus. Is expressed in axis; central nervous system; intestinal bulb; liver; and presumptive diencephalon. Orthologous to human NCOA1 (nuclear receptor coactivator 1).
Genome Resources: Alliance (1),  Gene:563288 (1),  Ensembl(GRCz11):ENSDARG00000018257 (2)
GENE EXPRESSION
All Expression Data: 14 figures from 3 publications
Directly Submitted Expression Data: 7 figures (7 images) from Thisse et al., 2008 [dq017644]
  6 figures (7 images) from Thisse et al., 2005 [eu1590]
Wild-type Stages, Structures: Gastrula:50%-epiboly (5.25h-5.66h) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
 
High Throughput Expression: Expression Atlas (1)
DISEASE ASSOCIATED WITH ncoa1 HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH ncoa1 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process regulation of transcription, DNA-templated (more)
Cellular Component nucleus (more)
Molecular Function nuclear hormone receptor binding (more)
GO Terms (all 9)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA ncoa1-202 (1)    Ensembl 5926
Browsers: NCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM ncoa1 No data available
MARKER RELATIONSHIPS
ncoa1 Contained in: [BAC] DKEY-5G7 (1) (order this), DKEY-34F16 (1) (order this)
ncoa1 Encodes: [EST] dq017644 (1), eu1590 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:XM_686652 (1) 4134 nt
Genomic GenBank:BX248390 (1) 239874 nt Blast at MegaBLAST
Polypeptide UniProtKB:Q5RIG3 (1) 1349 aa
Sequence Information (all 24)
ORTHOLOGY for ncoa1 ( Chr: 20 )
CITATIONS (38)