ZFIN is now using GRCz12tu for Genomic Data
Gene
opcml
- ID
- ZDB-GENE-040927-3
- Name
- opioid binding protein/cell adhesion molecule-like
- Symbol
- opcml Nomenclature History
- Previous Names
-
- zgc:92901
- Type
- protein_coding_gene
- Location
- Chr: 10 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to be involved in heterophilic cell-cell adhesion and regulation of synapse assembly. Predicted to be active in plasma membrane. Is expressed in nervous system and otic vesicle. Human ortholog(s) of this gene implicated in hypertension; ovarian cancer; and primary open angle glaucoma. Orthologous to several human genes including OPCML (opioid binding protein/cell adhesion molecule like).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 10 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cssl:d0634 (17 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| ovarian cancer | Alliance | Ovarian cancer, somatic | 167000 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR003598 | Immunoglobulin subtype 2 |
| Domain | IPR003599 | Immunoglobulin domain subtype |
| Domain | IPR007110 | Immunoglobulin-like domain |
| Domain | IPR013098 | Immunoglobulin I-set |
| Domain | IPR013106 | Immunoglobulin V-set domain |
| Family | IPR050876 | IgLON domain-containing protein |
| Homologous_superfamily | IPR013783 | Immunoglobulin-like fold |
| Homologous_superfamily | IPR036179 | Immunoglobulin-like domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | IgLON domain-containing protein | Immunoglobulin domain subtype | Immunoglobulin I-set | Immunoglobulin-like domain | Immunoglobulin-like domain superfamily | Immunoglobulin-like fold | Immunoglobulin subtype 2 | Immunoglobulin V-set domain |
|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M3B6A2 | InterPro | 335 | ||||||||
| UniProtKB:Q642G9 | InterPro | 342 | ||||||||
| UniProtKB:A0AB32U1C1 | InterPro | 316 | ||||||||
| UniProtKB:A0AC58GJG4 | InterPro | 190 | ||||||||
| UniProtKB:A0AC58GJG6 | InterPro | 190 | ||||||||
| UniProtKB:A0AC58GJI2 | InterPro | 341 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers